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title: "Nature 2021 — all accepted papers, page 4 — the most cited first"
description: "All 3,641 papers of Nature 2021 · page 4 of 37, the most cited first; those with our summary link to it."
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# Nature 2021: all accepted papers

3,641 papers · page 4 of 37 · the most cited first · [← Nature 2021](https://md.research.elamur.ai/free/en/venues/nature/2021/)

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301. **[Astrocytic interleukin-3 programs microglia and limits Alzheimer’s disease ↗](https://doi.org/10.1038/s41586-021-03734-6)**Cameron S. McAlpine, Joseph Park, Ana Griciuc et al.*322 citations*
302. **[Evaluating eligibility criteria of oncology trials using real-world data and AI ↗](https://doi.org/10.1038/s41586-021-03430-5)**Ruishan Liu, Shemra Rizzo, Samuel Whipple et al.*322 citations*
303. **[Topological complex-energy braiding of non-Hermitian bands ↗](https://doi.org/10.1038/s41586-021-03848-x)**Kai Wang, Avik Dutt, Charles C. Wojcik et al.*322 citations*
304. **[Excitons and emergent quantum phenomena in stacked 2D semiconductors ↗](https://doi.org/10.1038/s41586-021-03979-1)**Nathan P. Wilson, Wang Yao, Jie Shan et al.*319 citations*
305. **[A gene–environment-induced epigenetic program initiates tumorigenesis ↗](https://doi.org/10.1038/s41586-020-03147-x)**Direna Alonso‐Curbelo, Yu-Jui Ho, Cassandra Burdziak et al.*316 citations*
306. **[Pauli-limit violation and re-entrant superconductivity in moiré graphene ↗](https://doi.org/10.1038/s41586-021-03685-y)**Yuan Cao, Jeong Min Park, Kenji Watanabe et al.*316 citations*
307. **[Representational drift in primary olfactory cortex ↗](https://doi.org/10.1038/s41586-021-03628-7)**Carl Edward Schoonover, Sarah N. Ohashi, Richard Axel et al.*313 citations*
308. **[Enabling conditions for an equitable and sustainable blue economy ↗](https://doi.org/10.1038/s41586-021-03327-3)**Andrés Miguel Cisneros-Montemayor, Marcia Moreno‐Báez, Gabriel Reygondeau et al.*312 citations*
309. **[Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans ↗](https://doi.org/10.1038/s41586-021-03681-2)**Galit Alter, Jingyou Yu, Jinyan Liu et al.*312 citations*
310. **[Quantum criticality in twisted transition metal dichalcogenides ↗](https://doi.org/10.1038/s41586-021-03815-6)**Augusto Ghiotto, En-Min Shih, Giancarlo Pereira et al.*312 citations*
311. **[Giant nonlinear optical responses from photon-avalanching nanoparticles ↗](https://doi.org/10.1038/s41586-020-03092-9)**Changhwan Lee, Emma Z. Xu, Yawei Liu et al.*310 citations*
312. **[Targeting SWI/SNF ATPases in enhancer-addicted prostate cancer ↗](https://doi.org/10.1038/s41586-021-04246-z)**Lanbo Xiao, Abhijit Parolia, Yuanyuan Qiao et al.*310 citations*
313. **[Non-KREEP origin for Chang’e-5 basalts in the Procellarum KREEP Terrane ↗](https://doi.org/10.1038/s41586-021-04119-5)**Heng‐Ci Tian, Hao Wang, Yi g Chen et al.*309 citations*
314. **[Antibody epitopes in vaccine-induced immune thrombotic thrombocytopaenia ↗](https://doi.org/10.1038/s41586-021-03744-4)**Angela Huynh, John G. Kelton, Donald M. Arnold et al.*308 citations*
315. **[Dietary palmitic acid promotes a prometastatic memory via Schwann cells ↗](https://doi.org/10.1038/s41586-021-04075-0)**Gloria Pascual, Diana Domínguez, Marc Elosua-Bayés et al.*308 citations*
316. **[Low glycaemic diets alter lipid metabolism to influence tumour growth ↗](https://doi.org/10.1038/s41586-021-04049-2)**Evan C. Lien, Anna M. Westermark, Yin Zhang et al.*308 citations*
317. **[CMOS-based cryogenic control of silicon quantum circuits ↗](https://doi.org/10.1038/s41586-021-03469-4)**Xiao Xue, Bishnu Patra, Jeroen P. G. van Dijk et al.*306 citations*
318. **[High-order superlattices by rolling up van der Waals heterostructures ↗](https://doi.org/10.1038/s41586-021-03338-0)**Bei Zhao, Zhong Wan, Yuan Liu et al.*306 citations*
319. **[Local immune response to food antigens drives meal-induced abdominal pain ↗](https://doi.org/10.1038/s41586-020-03118-2)**Javier Aguilera‐Lizarraga, Morgane V. Florens, Maria Francesca Viola et al.*306 citations*
320. **[Anatomically distinct fibroblast subsets determine skin autoimmune patterns ↗](https://doi.org/10.1038/s41586-021-04221-8)**Zijian Xu, Daoming Chen, Yucheng Hu et al.*305 citations*
321. **[Structure of pathological TDP-43 filaments from ALS with FTLD ↗](https://doi.org/10.1038/s41586-021-04199-3)**Diana Arseni, Masato Hasegawa, Alexey G. Murzin et al.*305 citations*
322. **[Quadrivalent influenza nanoparticle vaccines induce broad protection ↗](https://doi.org/10.1038/s41586-021-03365-x)**Seyhan Boyoglu-Barnum, Daniel Ellis, Rebecca A. Gillespie et al.*304 citations*
323. **[The mouse cortico–basal ganglia–thalamic network ↗](https://doi.org/10.1038/s41586-021-03993-3)**Nicholas N. Foster, Joshua Barry, Laura Korobkova et al.*304 citations*
324. **[A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis ↗](https://doi.org/10.1038/s41586-021-03298-5)**Bo Shen, Alpaslan Tasdogan, Jessalyn M. Ubellacker et al.*303 citations*
325. **[The structural basis of odorant recognition in insect olfactory receptors ↗](https://doi.org/10.1038/s41586-021-03794-8)**Josefina Inés del Mármol, Mackenzie A. Yedlin, Vanessa Ruta*302 citations*
326. **[Bulk–disclination correspondence in topological crystalline insulators ↗](https://doi.org/10.1038/s41586-020-03125-3)**Yang Liu, Shuwai Leung, Feifei Li et al.*299 citations*
327. **[High-frequency and intrinsically stretchable polymer diodes ↗](https://doi.org/10.1038/s41586-021-04053-6)**Naoji Matsuhisa, Simiao Niu, Stephen J. K. O’Neill et al.*299 citations*
328. **[The three major axes of terrestrial ecosystem function ↗](https://doi.org/10.1038/s41586-021-03939-9)**Mirco Migliavacca, Talie Musavi, Miguel D. Mahecha et al.*299 citations*
329. **[Interface nano-optics with van der Waals polaritons ↗](https://doi.org/10.1038/s41586-021-03581-5)**Qing Zhang, Guangwei Hu, Weiliang Ma et al.*298 citations*
330. **[Near-complete depolymerization of polyesters with nano-dispersed enzymes ↗](https://doi.org/10.1038/s41586-021-03408-3)**Christopher DelRe, Yufeng Jiang, Philjun Kang et al.*298 citations*
331. **[Lectins enhance SARS-CoV-2 infection and influence neutralizing antibodies ↗](https://doi.org/10.1038/s41586-021-03925-1)**Florian A. Lempp, Leah B. Soriaga, Martin Montiel-Ruiz et al.*297 citations*
332. **[The contribution of insects to global forest deadwood decomposition ↗](https://doi.org/10.1038/s41586-021-03740-8)**Sebastian Seibold, Werner Rammer, Torsten Hothorn et al.*296 citations*
333. **[m6A RNA methylation regulates the fate of endogenous retroviruses ↗](https://doi.org/10.1038/s41586-020-03135-1)**Tomasz Chełmicki, Emeline Roger, Aurélie Teissandier et al.*295 citations*
334. **[Whole-cell organelle segmentation in volume electron microscopy ↗](https://doi.org/10.1038/s41586-021-03977-3)**Larissa Heinrich, Davis Bennett, David Ackerman et al.*292 citations*
335. **[Delta coronavirus variant: scientists brace for impact ↗](https://doi.org/10.1038/d41586-021-01696-3)**Ewen Callaway*291 citations*
336. **[A bimodal burst energy distribution of a repeating fast radio burst source ↗](https://doi.org/10.1038/s41586-021-03878-5)**Di Li, Pei Wang, Weiwei Zhu et al.*290 citations*
337. **[Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition ↗](https://doi.org/10.1038/s41586-020-03114-6)**Yael Cohen‐Sharir, James M. McFarland, Mai Abdusamad et al.*290 citations*
338. **[Bubble casting soft robotics ↗](https://doi.org/10.1038/s41586-021-04029-6)**Trevor J. Jones, Etienne Jambon-Puillet, Joël Marthelot et al.*290 citations*
339. **[Electric cars and batteries: how will the world produce enough? ↗](https://doi.org/10.1038/d41586-021-02222-1)**Davide Castelvecchi*290 citations*
340. **[eccDNAs are apoptotic products with high innate immunostimulatory activity ↗](https://doi.org/10.1038/s41586-021-04009-w)**Yuangao Wang, Meng Wang, Mohamed Nadhir Djekidel et al.*290 citations*
341. **[Actively variable-spectrum optoelectronics with black phosphorus ↗](https://doi.org/10.1038/s41586-021-03701-1)**Hyung‐Jin Kim, Shiekh Zia Uddin, Der‐Hsien Lien et al.*289 citations*
342. **[Mechanical computing ↗](https://doi.org/10.1038/s41586-021-03623-y)**Hiromi Yasuda, Philip R. Buskohl, Andrew S. Gillman et al.*287 citations*
343. **[Dietary fructose improves intestinal cell survival and nutrient absorption ↗](https://doi.org/10.1038/s41586-021-03827-2)**Samuel R. Taylor, Shakti Ramsamooj, Roger J. Liang et al.*286 citations*
344. **[Double-helical assembly of heterodimeric nanoclusters into supercrystals ↗](https://doi.org/10.1038/s41586-021-03564-6)**Yingwei Li, Meng Ran Zhou, Yongbo Song et al.*286 citations*
345. **[Perovskite-type superlattices from lead halide perovskite nanocubes ↗](https://doi.org/10.1038/s41586-021-03492-5)**Ihor Cherniukh, Gabriele Rainò, Thilo Stöferle et al.*286 citations*
346. **[TMK-based cell-surface auxin signalling activates cell-wall acidification ↗](https://doi.org/10.1038/s41586-021-03976-4)**Wenwei Lin, Xiang Zhou, Wenxin Tang et al.*286 citations*
347. **[Observation of fractional edge excitations in nanographene spin chains ↗](https://doi.org/10.1038/s41586-021-03842-3)**Shantanu Mishra, Gonçalo Catarina, Fu‐Peng Wu et al.*284 citations*
348. **[Human neocortical expansion involves glutamatergic neuron diversification ↗](https://doi.org/10.1038/s41586-021-03813-8)**Jim Berg, Staci A. Sorensen, Jonathan T. Ting et al.*283 citations*
349. **[Telecom-heralded entanglement between multimode solid-state quantum memories ↗](https://doi.org/10.1038/s41586-021-03481-8)**Dario Lago-Rivera, Samuele Grandi, Jelena V. Rakonjac et al.*283 citations*
350. **[DNA methylation atlas of the mouse brain at single-cell resolution ↗](https://doi.org/10.1038/s41586-020-03182-8)**Hanqing Liu, Jingtian Zhou, Wei Tian et al.*279 citations*
351. **[Single-cell epigenomics reveals mechanisms of human cortical development ↗](https://doi.org/10.1038/s41586-021-03209-8)**Ryan S. Ziffra, Chang N. Kim, Jayden M. Ross et al.*278 citations*
352. **[An atlas of cortical arealization identifies dynamic molecular signatures ↗](https://doi.org/10.1038/s41586-021-03910-8)**Aparna Bhaduri, Carmen Sandoval-Espinosa, Marcos Otero‐García et al.*277 citations*
353. **[How bad is Omicron? What scientists know so far ↗](https://doi.org/10.1038/d41586-021-03614-z)**Ewen Callaway, Heidi K. Ledford*277 citations*
354. **[A natively flexible 32-bit Arm microprocessor ↗](https://doi.org/10.1038/s41586-021-03625-w)**John Biggs, James Myers, Jedrzej Kufel et al.*276 citations*
355. **[Ultrahard bulk amorphous carbon from collapsed fullerene ↗](https://doi.org/10.1038/s41586-021-03882-9)**Yuchen Shang, Zhaodong Liu, Jiajun Dong et al.*276 citations*
356. **[Anti-SARS-CoV-2 receptor-binding domain antibody evolution after mRNA vaccination ↗](https://doi.org/10.1038/s41586-021-04060-7)**Alice Cho, Frauke Muecksch, Dennis J. Schaefer-Babajew et al.*275 citations*
357. **[Chaperone-mediated autophagy sustains haematopoietic stem-cell function ↗](https://doi.org/10.1038/s41586-020-03129-z)**Shuxian Dong, Qian Wang, Yun-Ruei Kao et al.*274 citations*
358. **[Whole-genome doubling confers unique genetic vulnerabilities on tumour cells ↗](https://doi.org/10.1038/s41586-020-03133-3)**Ryan J. Quinton, Amanda DiDomizio, Marc A. Vittoria et al.*274 citations*
359. **[Wetting regulates autophagy of phase-separated compartments and the cytosol ↗](https://doi.org/10.1038/s41586-020-2992-3)**Jaime Agudo‐Canalejo, Sebastian Wolfgang Schultz, Haruka Chino et al.*273 citations*
360. **[The epidemiological impact of the NHS COVID-19 app ↗](https://doi.org/10.1038/s41586-021-03606-z)**Chris Wymant, Luca Ferretti A, Daphne Tsallis et al.*272 citations*
361. **[Correlation-driven topological phases in magic-angle twisted bilayer graphene ↗](https://doi.org/10.1038/s41586-020-03159-7)**Youngjoon Choi, Hyunjin Kim, Yang Peng et al.*271 citations*
362. **[Structural insights into the lipid and ligand regulation of serotonin receptors ↗](https://doi.org/10.1038/s41586-021-03376-8)**Peiyu Xu, Sijie Huang, Huibing Zhang et al.*270 citations*
363. **[Cellular anatomy of the mouse primary motor cortex ↗](https://doi.org/10.1038/s41586-021-03970-w)**Rodrigo Muñoz-Castañeda, Brian Zingg, Katherine S. Matho et al.*267 citations*
364. **[Dynamic spatial progression of isolated lithium during battery operations ↗](https://doi.org/10.1038/s41586-021-04168-w)**Fang Liu, Rong Xu, Yecun Wu et al.*267 citations*
365. **[KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements ↗](https://doi.org/10.1038/s41586-021-03994-2)**Shang‐Min Zhang, Wesley L. Cai, Xiaoni Liu et al.*267 citations*
366. **[Spatial genomics enables multi-modal study of clonal heterogeneity in tissues ↗](https://doi.org/10.1038/s41586-021-04217-4)**Tongtong Zhao, Zachary Chiang, Julia W. Morriss et al.*267 citations*
367. **[Broad sarbecovirus neutralization by a human monoclonal antibody ↗](https://doi.org/10.1038/s41586-021-03817-4)**M. Alejandra Tortorici, Nadine Czudnochowski, Tyler N. Starr et al.*266 citations*
368. **[Oxytocin neurons enable social transmission of maternal behaviour ↗](https://doi.org/10.1038/s41586-021-03814-7)**Ioana Carcea, Naomi López Caraballo, Bianca Jones Marlin et al.*265 citations*
369. **[Overshooting tipping point thresholds in a changing climate ↗](https://doi.org/10.1038/s41586-021-03263-2)**Paul David Longden Ritchie, Joseph J. Clarke, Peter M. Cox et al.*263 citations*
370. **[Concrete needs to lose its colossal carbon footprint ↗](https://doi.org/10.1038/d41586-021-02612-5)***262 citations*
371. **[Operando optical tracking of single-particle ion dynamics in batteries ↗](https://doi.org/10.1038/s41586-021-03584-2)**Alice J. Merryweather, Christoph Schnedermann, Quentin Jacquet et al.*262 citations*
372. **[Widespread phytoplankton blooms triggered by 2019–2020 Australian wildfires ↗](https://doi.org/10.1038/s41586-021-03805-8)**Weiyi Tang, Joan Llort, Jakob Weis et al.*262 citations*
373. **[Programmable RNA targeting with the single-protein CRISPR effector Cas7-11 ↗](https://doi.org/10.1038/s41586-021-03886-5)**Ahsen Özcan, Rohan N. Krajeski, Eleonora I. Ioannidi et al.*261 citations*
374. **[SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells ↗](https://doi.org/10.1038/s41586-021-04025-w)**Ying Wang, Frederick S. Yen, Xiphias Ge Zhu et al.*261 citations*
375. **[Strongly correlated excitonic insulator in atomic double layers ↗](https://doi.org/10.1038/s41586-021-03947-9)**Liguo Ma, Phuong X. Nguyen, Zefang Wang et al.*261 citations*
376. **[De novo design of modular and tunable protein biosensors ↗](https://doi.org/10.1038/s41586-021-03258-z)**Alfredo Quijano‐Rubio, Andy Hsien-Wei Yeh, Jooyoung Park et al.*257 citations*
377. **[Facile route to bulk ultrafine-grain steels for high strength and ductility ↗](https://doi.org/10.1038/s41586-021-03246-3)**Junheng Gao, Suihe Jiang, H. R. Zhang et al.*257 citations*
378. **[SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis ↗](https://doi.org/10.1038/s41586-021-03610-3)**Yaara Finkel, Avi Gluck, Aharon Nachshon et al.*257 citations*
379. **[Global absence and targeting of protective immune states in severe COVID-19 ↗](https://doi.org/10.1038/s41586-021-03234-7)**Alexis J. Combes, Tristan Courau, Nicholas F. Kuhn et al.*256 citations*
380. **[Rechargeable Na/Cl2 and Li/Cl2 batteries ↗](https://doi.org/10.1038/s41586-021-03757-z)**Guanzhou Zhu, Xin Tian, Hung‐Chun Tai et al.*256 citations*
381. **[Widespread woody plant use of water stored in bedrock ↗](https://doi.org/10.1038/s41586-021-03761-3)**Erica L. McCormick, David Dralle, W. Jesse Hahm et al.*256 citations*
382. **[A COVID-19 peptide vaccine for the induction of SARS-CoV-2 T cell immunity ↗](https://doi.org/10.1038/s41586-021-04232-5)**Jonas S. Heitmann, Tatjana Bilich, Claudia Tandler et al.*255 citations*
383. **[Cell surface and intracellular auxin signalling for H+ fluxes in root growth ↗](https://doi.org/10.1038/s41586-021-04037-6)**Lanxin Li, Inge Verstraeten, Mark Roosjen et al.*255 citations*
384. **[Intrinsic toughening and stable crack propagation in hexagonal boron nitride ↗](https://doi.org/10.1038/s41586-021-03488-1)**Yingchao Yang, Zhigong Song, Guangyuan Lu et al.*255 citations*
385. **[A chickpea genetic variation map based on the sequencing of 3,366 genomes ↗](https://doi.org/10.1038/s41586-021-04066-1)**Rajeev Kumar Varshney, Manish Roorkiwal, Shuai Sun et al.*254 citations*
386. **[Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift ↗](https://doi.org/10.1038/d41586-021-03825-4)**Elisabetta Cameroni, John E. Bowen, Laura E. Rosen et al.*254 citations*
387. **[An autoimmune stem-like CD8 T cell population drives type 1 diabetes ↗](https://doi.org/10.1038/s41586-021-04248-x)**Sofia V. Gearty, Friederike Dündar, Paul Zumbo et al.*253 citations*
388. **[Breast tumours maintain a reservoir of subclonal diversity during expansion ↗](https://doi.org/10.1038/s41586-021-03357-x)**Darlan Conterno Minussi, Michael D. Nicholson, Hanghui Ye et al.*253 citations*
389. **[NOTUM from Apc-mutant cells biases clonal competition to initiate cancer ↗](https://doi.org/10.1038/s41586-021-03525-z)**Dustin James Flanagan, Nalle Pentinmikko, Kalle Luopajärvi et al.*253 citations*
390. **[Ghost hyperbolic surface polaritons in bulk anisotropic crystals ↗](https://doi.org/10.1038/s41586-021-03755-1)**Weiliang Ma, Guangwei Hu, Debo Hu et al.*252 citations*
391. **[Neutralizing antibody vaccine for pandemic and pre-emergent coronaviruses ↗](https://doi.org/10.1038/s41586-021-03594-0)**Kevin O. Saunders, Esther Lee, Robert Parks et al.*252 citations*
392. **[NF1 mutation drives neuronal activity-dependent initiation of optic glioma ↗](https://doi.org/10.1038/s41586-021-03580-6)**Yuan Xiang Pan, Jared D. Hysinger, Tara Barron et al.*251 citations*
393. **[Untimely TGFβ responses in COVID-19 limit antiviral functions of NK cells ↗](https://doi.org/10.1038/s41586-021-04142-6)**Mario Witkowski, Caroline Tizian, Marta Ferreira‐Gomes et al.*250 citations*
394. **[Megastudies improve the impact of applied behavioural science ↗](https://doi.org/10.1038/s41586-021-04128-4)**Katherine L. Milkman, Dena M. Gromet, Hung Ho et al.*249 citations*
395. **[Photoinduced copper-catalysed asymmetric amidation via ligand cooperativity ↗](https://doi.org/10.1038/s41586-021-03730-w)**Caiyou Chen, Jonas C. Peters, Gregory C. Fu*249 citations*
396. **[STING controls nociception via type I interferon signalling in sensory neurons ↗](https://doi.org/10.1038/s41586-020-03151-1)**Christopher R. Donnelly, Changyu Jiang, Amanda Sara Andriessen et al.*249 citations*
397. **[IgA transcytosis and antigen recognition govern ovarian cancer immunity ↗](https://doi.org/10.1038/s41586-020-03144-0)**Subir Biswas, Gunjan Mandal, Kyle K. Payne et al.*248 citations*
398. **[The fight against fake-paper factories that churn out sham science ↗](https://doi.org/10.1038/d41586-021-00733-5)**Holly Else, Richard Van Noorden*248 citations*
399. **[Unrepresentative big surveys significantly overestimated US vaccine uptake ↗](https://doi.org/10.1038/s41586-021-04198-4)**Valerie C. Bradley, Shiro Kuriwaki, Michael Isakov et al.*248 citations*
400. **[Ex utero mouse embryogenesis from pre-gastrulation to late organogenesis ↗](https://doi.org/10.1038/s41586-021-03416-3)**Alejandro Aguilera-Castrejon, Bernardo Oldak, Tom Shani et al.*247 citations*

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