---
title: "Nature 2022 — all accepted papers, page 5 — the most cited first"
description: "All 3,983 papers of Nature 2022 · page 5 of 40, the most cited first; those with our summary link to it."
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# Nature 2022: all accepted papers

3,983 papers · page 5 of 40 · the most cited first · [← Nature 2022](https://md.research.elamur.ai/free/en/venues/nature/2022/)

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401. **[Phytocytokine signalling reopens stomata in plant immunity and water loss ↗](https://doi.org/10.1038/s41586-022-04684-3)**Zunyong Liu, Shuguo Hou, Olivier Rodrigues et al.*199 citations*
402. **[Teixobactin kills bacteria by a two-pronged attack on the cell envelope ↗](https://doi.org/10.1038/s41586-022-05019-y)**Rhythm Shukla, Francesca Lavore, Sourav Maity et al.*199 citations*
403. **[Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 ↗](https://doi.org/10.1038/s41586-022-04722-0)**Tal Iram, Fabian Kern, Achint Kaur et al.*199 citations*
404. **[Structural basis of NPR1 in activating plant immunity ↗](https://doi.org/10.1038/s41586-022-04699-w)**Shivesh Kumar, Raul Zavaliev, Qinglin Wu et al.*198 citations*
405. **[Aquaculture will continue to depend more on land than sea ↗](https://doi.org/10.1038/s41586-021-04331-3)**Wenbo Zhang, Ben Belton, Peter Edwards et al.*196 citations*
406. **[Cumulative polarization in conductive interfacial ferroelectrics ↗](https://doi.org/10.1038/s41586-022-05341-5)**Swarup Deb, Wei Cao, Noam Raab et al.*196 citations*
407. **[Identification of carbon dioxide in an exoplanet atmosphere ↗](https://doi.org/10.1038/s41586-022-05269-w)**JWST Transiting Exoplanet Community Early Release Science Team, Eva-Maria Ahrer, Lili Alderson et al.*196 citations*
408. **[Landscape of helper and regulatory antitumour CD4+ T cells in melanoma ↗](https://doi.org/10.1038/s41586-022-04682-5)**Giacomo Oliveira, Kari Stromhaug, Nicoletta Cieri et al.*196 citations*
409. **[Structures of a phycobilisome in light-harvesting and photoprotected states ↗](https://doi.org/10.1038/s41586-022-05156-4)**María Agustina Domínguez-Martín, Paul Victor Sauer, Henning Kirst et al.*196 citations*
410. **[Actin cytoskeleton and complex cell architecture in an Asgard archaeon ↗](https://doi.org/10.1038/s41586-022-05550-y)**Thiago Rodrigues-Oliveira, Florian Wollweber, Rafael I. Ponce-Toledo et al.*195 citations*
411. **[Unbiasing fermionic quantum Monte Carlo with a quantum computer ↗](https://doi.org/10.1038/s41586-021-04351-z)**William J. Huggins, Bryan O’Gorman, Nicholas C. Rubin et al.*195 citations*
412. **[A time-resolved, multi-symbol molecular recorder via sequential genome editing ↗](https://doi.org/10.1038/s41586-022-04922-8)**Junhong Choi, Wei Chen, Anna Minkina et al.*193 citations*
413. **[Age-dependent formation of TMEM106B amyloid filaments in human brains ↗](https://doi.org/10.1038/s41586-022-04650-z)**Manuel Schweighauser, Diana Arseni, Mehtap Bacioglu et al.*193 citations*
414. **[Pyrimidine inhibitors synergize with nucleoside analogues to block SARS-CoV-2 ↗](https://doi.org/10.1038/s41586-022-04482-x)**D. Schultz, Robert M. Johnson, Kasirajan Ayyanathan et al.*193 citations*
415. **[ABO genotype alters the gut microbiota by regulating GalNAc levels in pigs ↗](https://doi.org/10.1038/s41586-022-04769-z)**Hui Yang, Jinyuan Wu, Xiaochang Huang et al.*189 citations*
416. **[Machine learning and phone data can improve targeting of humanitarian aid ↗](https://doi.org/10.1038/s41586-022-04484-9)**Emily Aiken, Suzanne Bellue, Dean Karlan et al.*189 citations*
417. **[The pandemic’s true death toll: millions more than official counts ↗](https://doi.org/10.1038/d41586-022-00104-8)**David Adam*189 citations*
418. **[Long-primed germinal centres with enduring affinity maturation and clonal migration ↗](https://doi.org/10.1038/s41586-022-05216-9)**Jeong Hyun Lee, Henry J. Sutton, Christopher A. Cottrell et al.*188 citations*
419. **[RNA profiles reveal signatures of future health and disease in pregnancy ↗](https://doi.org/10.1038/s41586-021-04249-w)**Morten Rasmussen, Mitsu Reddy, Rory Nolan et al.*188 citations*
420. **[Activation of STING by targeting a pocket in the transmembrane domain ↗](https://doi.org/10.1038/s41586-022-04559-7)**Defen Lu, Guijun Shang, Jie Li et al.*187 citations*
421. **[Biocatalytic oxidative cross-coupling reactions for biaryl bond formation ↗](https://doi.org/10.1038/s41586-021-04365-7)**Lara E. Zetzsche, Jessica A. Yazarians, Suman Chakrabarty et al.*187 citations*
422. **[Transcriptional coupling of distant regulatory genes in living embryos ↗](https://doi.org/10.1038/s41586-022-04680-7)**Michal Levo, João Raimundo, Xinyang Bing et al.*187 citations*
423. **[Group A Streptococcus induces GSDMA-dependent pyroptosis in keratinocytes ↗](https://doi.org/10.1038/s41586-022-04717-x)**Doris L. LaRock, Anders F. Johnson, Shyra Wilde et al.*186 citations*
424. **[Deep whole-genome ctDNA chronology of treatment-resistant prostate cancer ↗](https://doi.org/10.1038/s41586-022-04975-9)**Cameron Herberts, Matti Annala, Joonatan Sipola et al.*185 citations*
425. **[Inflammatory memory and tissue adaptation in sickness and in health ↗](https://doi.org/10.1038/s41586-022-04919-3)**Shruti Naik, Elaine V. Fuchs*185 citations*
426. **[Optimal metrology with programmable quantum sensors ↗](https://doi.org/10.1038/s41586-022-04435-4)**Christian D. Marciniak, Thomas Feldker, Ivan Pogorelov et al.*185 citations*
427. **[A highly distorted ultraelastic chemically complex Elinvar alloy ↗](https://doi.org/10.1038/s41586-021-04309-1)**Quanfeng He, J. G. Wang, Hsin‐An Chen et al.*184 citations*
428. **[Structural basis for directional chitin biosynthesis ↗](https://doi.org/10.1038/s41586-022-05244-5)**Wei Chen, Peng Cao, Yuansheng Liu et al.*184 citations*
429. **[An asymmetric sp3–sp3 cross-electrophile coupling using ‘ene’-reductases ↗](https://doi.org/10.1038/s41586-022-05167-1)**Haigen Fu, Jingzhe Cao, Tianzhang Qiao et al.*183 citations*
430. **[RNA editing underlies genetic risk of common inflammatory diseases ↗](https://doi.org/10.1038/s41586-022-05052-x)**Qin Li, Michael J. Gloudemans, Jonathan M. Geisinger et al.*182 citations*
431. **[Visualizing translation dynamics at atomic detail inside a bacterial cell ↗](https://doi.org/10.1038/s41586-022-05255-2)**Liang Xue, Swantje Lenz, Maria Zimmermann‐Kogadeeva et al.*182 citations*
432. **[What the war in Ukraine means for energy, climate and food ↗](https://doi.org/10.1038/d41586-022-00969-9)**Jeff Tollefson*182 citations*
433. **[A first update on mapping the human genetic architecture of COVID-19 ↗](https://doi.org/10.1038/s41586-022-04826-7)**COVID-19 Host Genetics Initiative, COVID-19 Host Genetics Initiative, Leadership et al.*181 citations*
434. **[A genome-scale screen for synthetic drivers of T cell proliferation ↗](https://doi.org/10.1038/s41586-022-04494-7)**Mateusz Legut, Zoran Z. Gajic, Maria Guarino et al.*181 citations*
435. **[Grey wolf genomic history reveals a dual ancestry of dogs ↗](https://doi.org/10.1038/s41586-022-04824-9)**Anders Bergström, David W. G. Stanton, Ulrike H. Taron et al.*181 citations*
436. **[Spatial genomics maps the structure, nature and evolution of cancer clones ↗](https://doi.org/10.1038/s41586-022-05425-2)**Artem Lomakin, Jessica Svedlund, Carina Strell et al.*181 citations*
437. **[Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion ↗](https://doi.org/10.1038/s41586-022-05006-3)**Ju-Qiong Wang, Liang-Liang Li, Ao Hu et al.*180 citations*
438. **[Phenotypic plasticity and genetic control in colorectal cancer evolution ↗](https://doi.org/10.1038/s41586-022-05311-x)**Jacob Househam, Timon Heide, George D. Cresswell et al.*180 citations*
439. **[Magneto-optical trapping and sub-Doppler cooling of a polyatomic molecule ↗](https://doi.org/10.1038/s41586-022-04620-5)**Nathaniel B. Vilas, Christian Hallas, Loïc Anderegg et al.*179 citations*
440. **[Stromal changes in the aged lung induce an emergence from melanoma dormancy ↗](https://doi.org/10.1038/s41586-022-04774-2)**Mitchell E. Fane, Yash Chhabra, Gretchen Marie Alicea et al.*179 citations*
441. **[The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron ↗](https://doi.org/10.1038/s41586-022-05333-5)**Saki Ichikawa, Hope A. Flaxman, Wenqing Xu et al.*179 citations*
442. **[Active eosinophils regulate host defence and immune responses in colitis ↗](https://doi.org/10.1038/s41586-022-05628-7)**Alessandra Gurtner, Costanza Borrelli, Ignacio Gonzalez-Perez et al.*178 citations*
443. **[THP9 enhances seed protein content and nitrogen-use efficiency in maize ↗](https://doi.org/10.1038/s41586-022-05441-2)**Yongcai Huang, Haihai Wang, Yidong Zhu et al.*178 citations*
444. **[A preoptic neuronal population controls fever and appetite during sickness ↗](https://doi.org/10.1038/s41586-022-04793-z)**Jessica A. Osterhout, Vikrant Kapoor, Stephen W. Eichhorn et al.*177 citations*
445. **[Eicosanoid signalling blockade protects middle-aged mice from severe COVID-19 ↗](https://doi.org/10.1038/s41586-022-04630-3)**Lok-Yin Roy Wong, Jian Hua Zheng, Kevin Wilhelmsen et al.*177 citations*
446. **[Lidar reveals pre-Hispanic low-density urbanism in the Bolivian Amazon ↗](https://doi.org/10.1038/s41586-022-04780-4)**Heiko Prümers, Carla Jaimes Betancourt, José Iriarte et al.*177 citations*
447. **[The Anglo-Saxon migration and the formation of the early English gene pool ↗](https://doi.org/10.1038/s41586-022-05247-2)**Joscha Gretzinger, Duncan Sayer, Pierre Justeau et al.*177 citations*
448. **[A year-round satellite sea-ice thickness record from CryoSat-2 ↗](https://doi.org/10.1038/s41586-022-05058-5)**Jack Landy, Geoffrey Dawson, Michel C. Tsamados et al.*176 citations*
449. **[Autoimmunity-associated T cell receptors recognize HLA-B*27-bound peptides ↗](https://doi.org/10.1038/s41586-022-05501-7)**Xinbo Yang, Lee I. Garner, Ivan V. Zvyagin et al.*176 citations*
450. **[Bacterial retrons encode phage-defending tripartite toxin–antitoxin systems ↗](https://doi.org/10.1038/s41586-022-05091-4)**Jacob Bobonis, Karin Mitosch, André Mateus et al.*176 citations*
451. **[Phage anti-CBASS and anti-Pycsar nucleases subvert bacterial immunity ↗](https://doi.org/10.1038/s41586-022-04716-y)**Samuel J. Hobbs, Tanita Wein, Allen Lu et al.*176 citations*
452. **[Self-regulated non-reciprocal motions in single-material microstructures ↗](https://doi.org/10.1038/s41586-022-04561-z)**Shucong Li, Michael M. Lerch, James T. Waters et al.*176 citations*
453. **[A prebiotically plausible scenario of an RNA–peptide world ↗](https://doi.org/10.1038/s41586-022-04676-3)**Felix Müller, Luis Escobar, Felix Xu et al.*175 citations*
454. **[Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants ↗](https://doi.org/10.1038/s41586-022-04466-x)**Kang Wang, Zijing Jia, Linilin Bao et al.*175 citations*
455. **[ABP1–TMK auxin perception for global phosphorylation and auxin canalization ↗](https://doi.org/10.1038/s41586-022-05187-x)**Jiřı́ Friml, Michelle Gallei, Zuzana Gelová et al.*174 citations*
456. **[Antarctic calving loss rivals ice-shelf thinning ↗](https://doi.org/10.1038/s41586-022-05037-w)**Chad A. Greene, Alex Gardner, Nicole‐Jeanne Schlegel et al.*174 citations*
457. **[A solid-state electrolysis process for upcycling aluminium scrap ↗](https://doi.org/10.1038/s41586-022-04748-4)**Xin Chun Lu, Zhengyang Zhang, Takehito Hiraki et al.*173 citations*
458. **[Diverse tsunamigenesis triggered by the Hunga Tonga-Hunga Ha’apai eruption ↗](https://doi.org/10.1038/s41586-022-05170-6)**Patrick Joseph Lynett, Maile P. McCann, Zili Zhou et al.*173 citations*
459. **[Optical observation of single spins in silicon ↗](https://doi.org/10.1038/s41586-022-04821-y)**Daniel B. Higginbottom, A. T. K. Kurkjian, Camille Chartrand et al.*173 citations*
460. **[Combination anti-HIV antibodies provide sustained virological suppression ↗](https://doi.org/10.1038/s41586-022-04797-9)**Michael C. Sneller, Jana Blažková, J. Shawn Justement et al.*172 citations*
461. **[Genetic insights into the social organization of Neanderthals ↗](https://doi.org/10.1038/s41586-022-05283-y)**Laurits Skov, Stéphane Peyrégne, Divyaratan Popli et al.*172 citations*
462. **[Quantum error correction with silicon spin qubits ↗](https://doi.org/10.1038/s41586-022-04986-6)**Kenta Takeda, Akito Noiri, Takashi Nakajima et al.*172 citations*
463. **[Traversable wormhole dynamics on a quantum processor ↗](https://doi.org/10.1038/s41586-022-05424-3)**Daniel Louis Jafferis, Alexander Zlokapa, Joseph David Lykken et al.*172 citations*
464. **[Direct activation of a bacterial innate immune system by a viral capsid protein ↗](https://doi.org/10.1038/s41586-022-05444-z)**Tong Zhang, Hedvig Tamman, Kyo Coppieters ’t Wallant et al.*171 citations*
465. **[Emergent charge order in pressurized kagome superconductor CsV3Sb5 ↗](https://doi.org/10.1038/s41586-022-05351-3)**Lixuan Zheng, Zhimian Wu, Ye Yang et al.*171 citations*
466. **[Entorhinal cortex directs learning-related changes in CA1 representations ↗](https://doi.org/10.1038/s41586-022-05378-6)**Christine Grienberger, Jeffrey C. Magee*171 citations*
467. **[Defining the risk of SARS-CoV-2 variants on immune protection ↗](https://doi.org/10.1038/s41586-022-04690-5)**Marciela M. DeGrace, Elodie Ghedin, Matthew B. Frieman et al.*170 citations*
468. **[Evaporation of microwave-shielded polar molecules to quantum degeneracy ↗](https://doi.org/10.1038/s41586-022-04900-0)**Andreas Schindewolf, Roman Bause, Xing-Yan Chen et al.*169 citations*
469. **[Mapping clustered mutations in cancer reveals APOBEC3 mutagenesis of ecDNA ↗](https://doi.org/10.1038/s41586-022-04398-6)**Erik N. Bergstrom, Jens Luebeck, Mia Petljak et al.*169 citations*
470. **[R-loop formation and conformational activation mechanisms of Cas9 ↗](https://doi.org/10.1038/s41586-022-05114-0)**Martin Pačesa, Luuk Loeff, Irma Querques et al.*169 citations*
471. **[Decoding gene regulation in the fly brain ↗](https://doi.org/10.1038/s41586-021-04262-z)**Jasper Janssens, Sara Aibar, Ibrahim Ihsan Taskiran et al.*168 citations*
472. **[Lifelong multilineage contribution by embryonic-born blood progenitors ↗](https://doi.org/10.1038/s41586-022-04804-z)**Sachin H Patel, Constantina Christodoulou, Caleb Weinreb et al.*168 citations*
473. **[A brainstem map for visceral sensations ↗](https://doi.org/10.1038/s41586-022-05139-5)**Ran Chen, Jack C. Boettcher, Judith A. Kaye et al.*167 citations*
474. **[A transcriptomic axis predicts state modulation of cortical interneurons ↗](https://doi.org/10.1038/s41586-022-04915-7)**Stéphane Bugeon, Joshua A. M. Duffield, Mario Dipoppa et al.*167 citations*
475. **[An integrated imaging sensor for aberration-corrected 3D photography ↗](https://doi.org/10.1038/s41586-022-05306-8)**Jiamin Wu, Yuduo Guo, Chao Deng et al.*167 citations*
476. **[Biosynthesis of strychnine ↗](https://doi.org/10.1038/s41586-022-04950-4)**Benke Hong, Dagny Grzech, Lorenzo Caputi et al.*167 citations*
477. **[cBAF complex components and MYC cooperate early in CD8+ T cell fate ↗](https://doi.org/10.1038/s41586-022-04849-0)**Ao Guo, Hongling Huang, Zhexin Zhu et al.*167 citations*
478. **[Genomics to select treatment for patients with metastatic breast cancer ↗](https://doi.org/10.1038/s41586-022-05068-3)**Fabrice André, Thomas Filleron, Maud T Kamal et al.*166 citations*
479. **[Search for Majorana neutrinos exploiting millikelvin cryogenics with CUORE ↗](https://doi.org/10.1038/s41586-022-04497-4)**D. Q. Adams, Christopher Alduino, K. Alfonso et al.*166 citations*
480. **[A dynamically reprogrammable surface with self-evolving shape morphing ↗](https://doi.org/10.1038/s41586-022-05061-w)**Yun Bai, Heling Wang, Yeguang Xue et al.*165 citations*
481. **[Brain–phenotype models fail for individuals who defy sample stereotypes ↗](https://doi.org/10.1038/s41586-022-05118-w)**Abigail S. Greene, Xilin Shen, Stephanie Noble et al.*165 citations*
482. **[Gut–brain circuits for fat preference ↗](https://doi.org/10.1038/s41586-022-05266-z)**Meng-Tong Li, Hwei-Ee Tan, Zhengyuan Lu et al.*165 citations*
483. **[Viruses inhibit TIR gcADPR signalling to overcome bacterial defence ↗](https://doi.org/10.1038/s41586-022-05375-9)**Azita Leavitt, Erez Yirmiya, Gil Amitai et al.*165 citations*
484. **[Boron clusters as broadband membrane carriers ↗](https://doi.org/10.1038/s41586-022-04413-w)**Andrea Barba‐Bon, Giulia Salluce, Irene Lostalé‐Seijo et al.*164 citations*
485. **[Divergent transcriptional regulation of astrocyte reactivity across disorders ↗](https://doi.org/10.1038/s41586-022-04739-5)**Joshua E. Burda, Timothy Mark O’Shea, Yan Ao et al.*164 citations*
486. **[Formation of moiré interlayer excitons in space and time ↗](https://doi.org/10.1038/s41586-022-04977-7)**David Schmitt, Jan Philipp Bange, Wiebke Bennecke et al.*163 citations*
487. **[Independent origins of fetal liver haematopoietic stem and progenitor cells ↗](https://doi.org/10.1038/s41586-022-05203-0)**Tomomasa Yokomizo, Takako Ideue, Saori Morino‐Koga et al.*163 citations*
488. **[A radio transient with unusually slow periodic emission ↗](https://doi.org/10.1038/s41586-021-04272-x)**Natasha Hurley-Walker, X. Zhang, Arash Bahramian et al.*162 citations*
489. **[Olfactory sensory experience regulates gliomagenesis via neuronal IGF1 ↗](https://doi.org/10.1038/s41586-022-04719-9)**Pengxiang Chen, Wei Wang, Rui Liu et al.*162 citations*
490. **[Programming multicellular assembly with synthetic cell adhesion molecules ↗](https://doi.org/10.1038/s41586-022-05622-z)**Adam J. Stevens, Andrew R. Harris, Josiah Gerdts et al.*162 citations*
491. **[Clathrin-associated AP-1 controls termination of STING signalling ↗](https://doi.org/10.1038/s41586-022-05354-0)**Ying Liu, Pengbiao Xu, Sophie Rivara et al.*161 citations*
492. **[Intralayer charge-transfer moiré excitons in van der Waals superlattices ↗](https://doi.org/10.1038/s41586-022-04991-9)**Mit H. Naik, Emma C. Regan, Zuocheng Zhang et al.*161 citations*
493. **[The size of the land carbon sink in China ↗](https://doi.org/10.1038/s41586-021-04255-y)**Yilong Wang, Xuhui Wang, Kai Wang et al.*161 citations*
494. **[A trispecific antibody targeting HER2 and T cells inhibits breast cancer growth via CD4 cells ↗](https://doi.org/10.1038/s41586-022-04439-0)**Edward Seung, Zhen Xing, Lan Wu et al.*160 citations*
495. **[Amyloid fibrils in FTLD-TDP are composed of TMEM106B and not TDP-43 ↗](https://doi.org/10.1038/s41586-022-04670-9)**Yi Xiao Jiang, Qin Cao, Michael R. Sawaya et al.*160 citations*
496. **[Antibody feedback regulates immune memory after SARS-CoV-2 mRNA vaccination ↗](https://doi.org/10.1038/s41586-022-05609-w)**Dennis J. Schaefer-Babajew, Zijun Wang, Frauke Muecksch et al.*160 citations*
497. **[Climate effects on archaic human habitats and species successions ↗](https://doi.org/10.1038/s41586-022-04600-9)**Axel Timmermann, Kyung‐Sook Yun, Pasquale Raia et al.*160 citations*
498. **[Cortical ensembles orchestrate social competition through hypothalamic outputs ↗](https://doi.org/10.1038/s41586-022-04507-5)**Nancy Padilla-Coreano, Kanha Batra, Makenzie Patarino et al.*160 citations*
499. **[Perovskite superlattices with efficient carrier dynamics ↗](https://doi.org/10.1038/s41586-022-04961-1)**Yusheng Lei, Yuheng Li, Chengchangfeng Lu et al.*160 citations*
500. **[Apoptotic brown adipocytes enhance energy expenditure via extracellular inosine ↗](https://doi.org/10.1038/s41586-022-05041-0)**Birte Niemann, Saskia Haufs-Brusberg, Laura Puetz et al.*159 citations*

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