---
title: "Nature 2022 — all accepted papers, page 6 — the most cited first"
description: "All 3,983 papers of Nature 2022 · page 6 of 40, the most cited first; those with our summary link to it."
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# Nature 2022: all accepted papers

3,983 papers · page 6 of 40 · the most cited first · [← Nature 2022](https://md.research.elamur.ai/free/en/venues/nature/2022/)

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501. **[Heterodimensional superlattice with in-plane anomalous Hall effect ↗](https://doi.org/10.1038/s41586-022-05031-2)**Jiadong Zhou, Jiadong Zhou, Wenjie Zhang et al.*159 citations*
502. **[Maternal inheritance of glucose intolerance via oocyte TET3 insufficiency ↗](https://doi.org/10.1038/s41586-022-04756-4)**Bin Chen, Yarui Du, Hong Zhu et al.*159 citations*
503. **[Scalable single-mode surface-emitting laser via open-Dirac singularities ↗](https://doi.org/10.1038/s41586-022-05021-4)**Rushin Contractor, Wanwoo Noh, Walid Redjem et al.*158 citations*
504. **[Within-host evolution of a gut pathobiont facilitates liver translocation ↗](https://doi.org/10.1038/s41586-022-04949-x)**Yi Yang, Mytien T. Nguyen, Varnica Khetrapal et al.*158 citations*
505. **[Failure of human rhombic lip differentiation underlies medulloblastoma formation ↗](https://doi.org/10.1038/s41586-022-05215-w)**Liam D. Hendrikse, Parthiv Haldipur, Olivier Saulnier et al.*157 citations*
506. **[Layered subsurface in Utopia Basin of Mars revealed by Zhurong rover radar ↗](https://doi.org/10.1038/s41586-022-05147-5)**Chao Li, Yikang Zheng, Xin Wang et al.*157 citations*
507. **[PIEZO1 transduces mechanical itch in mice ↗](https://doi.org/10.1038/s41586-022-04860-5)**Rose Z. Hill, Meaghan C. Loud, Adrienne E. Dubin et al.*157 citations*
508. **[Response of the East Antarctic Ice Sheet to past and future climate change ↗](https://doi.org/10.1038/s41586-022-04946-0)**Chris R. Stokes, Nerilie J. Abram, Michael J. Bentley et al.*157 citations*
509. **[Unified rhombic lip origins of group 3 and group 4 medulloblastoma ↗](https://doi.org/10.1038/s41586-022-05208-9)**Kyle S. Smith, Laure Bihannic, Brian L. Gudenas et al.*157 citations*
510. **[Ancient DNA and deep population structure in sub-Saharan African foragers ↗](https://doi.org/10.1038/s41586-022-04430-9)**Mark Lipson, Elizabeth Sawchuk, Jessica C. Thompson et al.*156 citations*
511. **[Where did Omicron come from? Three key theories ↗](https://doi.org/10.1038/d41586-022-00215-2)**Smriti Mallapaty*156 citations*
512. **[Close relatives of MERS-CoV in bats use ACE2 as their functional receptors ↗](https://doi.org/10.1038/s41586-022-05513-3)**Qing Xiong, Lei Cao, Chengbao Ma et al.*154 citations*
513. **[Dislocation-induced stop-and-go kinetics of interfacial transformations ↗](https://doi.org/10.1038/s41586-022-04880-1)**Xianhu Sun, Dongxiang Wu, Lianfeng Zou et al.*154 citations*
514. **[Brainstem ADCYAP1+ neurons control multiple aspects of sickness behaviour ↗](https://doi.org/10.1038/s41586-022-05161-7)**Anoj Ilanges, Rani Shiao, Jordan T. Shaked et al.*153 citations*
515. **[PLD3 affects axonal spheroids and network defects in Alzheimer’s disease ↗](https://doi.org/10.1038/s41586-022-05491-6)**Peng Yuan, Mengyang Zhang, Лей Тонг et al.*153 citations*
516. **[Electrophotocatalytic oxygenation of multiple adjacent C–H bonds ↗](https://doi.org/10.1038/s41586-022-05608-x)**Tristan Lambert, Tao Shen, Yi-Lun Li et al.*152 citations*
517. **[Molecular hallmarks of heterochronic parabiosis at single-cell resolution ↗](https://doi.org/10.1038/s41586-022-04461-2)**Róbert Pálovics, Andreas Keller, Nicholas Schaum et al.*152 citations*
518. **[Quantum cascade of correlated phases in trigonally warped bilayer graphene ↗](https://doi.org/10.1038/s41586-022-04937-1)**Α. Seiler, Fabian R. Geisenhof, Felix Winterer et al.*152 citations*
519. **[Adenylate cyclase activity of TIR1/AFB auxin receptors in plants ↗](https://doi.org/10.1038/s41586-022-05369-7)**Linlin Qi, Mateusz Kwiatkowski, Huihuang Chen et al.*151 citations*
520. **[Caspase-7 activates ASM to repair gasdermin and perforin pores ↗](https://doi.org/10.1038/s41586-022-04825-8)**Kengo Nozaki, Vivien Ileana Maltez, Manira Rayamajhi et al.*151 citations*
521. **[Compatibility rules of human enhancer and promoter sequences ↗](https://doi.org/10.1038/s41586-022-04877-w)**Drew T. Bergman, Thouis R. Jones, Vincent Liu et al.*151 citations*
522. **[Hippocampal place cells have goal-oriented vector fields during navigation ↗](https://doi.org/10.1038/s41586-022-04913-9)**Jake Ormond, John M. O'Keefe*151 citations*
523. **[Structures and mechanism of the plant PIN-FORMED auxin transporter ↗](https://doi.org/10.1038/s41586-022-04883-y)**Kien Lam Ung, Mikael Winkler, Lukas Schulz et al.*151 citations*
524. **[The tethered peptide activation mechanism of adhesion GPCRs ↗](https://doi.org/10.1038/s41586-022-04575-7)**Ximena Barros-Álvarez, Robert M. Nwokonko, Alexander Vizurraga et al.*151 citations*
525. **[Trends in Europe storm surge extremes match the rate of sea-level rise ↗](https://doi.org/10.1038/s41586-022-04426-5)**Francisco Mir Calafat, Thomas Wahl, Michael Getachew Tadesse et al.*151 citations*
526. **[An open science study of ageing in companion dogs ↗](https://doi.org/10.1038/s41586-021-04282-9)**Kate E. Creevy, Joshua M. Akey, Matt R. Kaeberlein et al.*150 citations*
527. **[Discovery of non-squalene triterpenes ↗](https://doi.org/10.1038/s41586-022-04773-3)**Hui Tao, Lukas Lauterbach, Guangkai Bian et al.*150 citations*
528. **[Historical glacier change on Svalbard predicts doubling of mass loss by 2100 ↗](https://doi.org/10.1038/s41586-021-04314-4)**Emily Geyman, WARD J. J. VAN PELT, Adam C. Maloof et al.*150 citations*
529. **[Identification of environmental factors that promote intestinal inflammation ↗](https://doi.org/10.1038/s41586-022-05308-6)**Liliana María Sanmarco, Chun‐Cheih Chao, Yu‐Chao Wang et al.*150 citations*
530. **[Impaired ketogenesis ties metabolism to T cell dysfunction in COVID-19 ↗](https://doi.org/10.1038/s41586-022-05128-8)**Fotios Karagiannis, Konrad Peukert, Laura Surace et al.*150 citations*
531. **[Spatial profiling of early primate gastrulation in utero ↗](https://doi.org/10.1038/s41586-022-04953-1)**Sophie Bergmann, Christopher A. Penfold, Erin M. Slatery et al.*150 citations*
532. **[Structural basis of actin filament assembly and aging ↗](https://doi.org/10.1038/s41586-022-05241-8)**Wout Oosterheert, Björn Udo Klink, Alexander Belyy et al.*150 citations*
533. **[Structures of the TMC-1 complex illuminate mechanosensory transduction ↗](https://doi.org/10.1038/s41586-022-05314-8)**Hanbin Jeong, Sarah Clark, April S. Goehring et al.*150 citations*
534. **[Chemotaxis shapes the microscale organization of the ocean’s microbiome ↗](https://doi.org/10.1038/s41586-022-04614-3)**Jean‐Baptiste Raina, Bennett S. Lambert, Donovan H. Parks et al.*149 citations*
535. **[Differential clock comparisons with a multiplexed optical lattice clock ↗](https://doi.org/10.1038/s41586-021-04344-y)**Xin Zheng, Jonathan Dolde, Varun Lochab et al.*149 citations*
536. **[Engineered jumpers overcome biological limits via work multiplication ↗](https://doi.org/10.1038/s41586-022-04606-3)**Elliot Wright Hawkes, Charles Xiao, Richard-Alexandre Peloquin et al.*149 citations*
537. **[Observing polymerization in 2D dynamic covalent polymers ↗](https://doi.org/10.1038/s41586-022-04409-6)**Gaolei Zhan, Zhen‐Feng Cai, Karol Strutyński et al.*149 citations*
538. **[Tryptophan depletion results in tryptophan-to-phenylalanine substitutants ↗](https://doi.org/10.1038/s41586-022-04499-2)**Abhijeet Pataskar, Julien Champagne, Remco Nagel et al.*148 citations*
539. **[Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae ↗](https://doi.org/10.1038/s41586-022-04546-y)**Milena Jaskólska, David William Adams, Melanie Blokesch*148 citations*
540. **[Genetic associations of protein-coding variants in human disease ↗](https://doi.org/10.1038/s41586-022-04394-w)**Benjamin B. Sun, Mitja Kurki, Christopher N. Foley et al.*147 citations*
541. **[Fos ensembles encode and shape stable spatial maps in the hippocampus ↗](https://doi.org/10.1038/s41586-022-05113-1)**Noah L. Pettit, Ee-Lynn Yap, Michael E. Greenberg et al.*146 citations*
542. **[Global Tonga tsunami explained by a fast-moving atmospheric source ↗](https://doi.org/10.1038/s41586-022-04926-4)**Rachid Omira, Ricardo S. Ramalho, Jihwan Kim et al.*146 citations*
543. **[MCM complexes are barriers that restrict cohesin-mediated loop extrusion ↗](https://doi.org/10.1038/s41586-022-04730-0)**Bart J. H. Dequeker, Matthias J Scherr, Hugo B. Brandão et al.*146 citations*
544. **[Pandemic-scale phylogenomics reveals the SARS-CoV-2 recombination landscape ↗](https://doi.org/10.1038/s41586-022-05189-9)**Yatish Turakhia, Bryan P. Thornlow, Angie S. Hinrichs et al.*146 citations*
545. **[SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry ↗](https://doi.org/10.1038/s41586-022-05282-z)**John Kee, Samuel Thudium, David M. Renner et al.*146 citations*
546. **[Structure, substrate recognition and initiation of hyaluronan synthase ↗](https://doi.org/10.1038/s41586-022-04534-2)**Finn P. Maloney, Jeremi Kuklewicz, Robin Adam Corey et al.*146 citations*
547. **[Super-enhancer hypermutation alters oncogene expression in B cell lymphoma ↗](https://doi.org/10.1038/s41586-022-04906-8)**Élodie Bal, Rahul Kumar, Mohammad Hadigol et al.*146 citations*
548. **[A complete temporal transcription factor series in the fly visual system ↗](https://doi.org/10.1038/s41586-022-04564-w)**Nikolaos Konstantinides, Isabel Holguera, Anthony M. Rossi et al.*145 citations*
549. **[Light-induced ferromagnetism in moiré superlattices ↗](https://doi.org/10.1038/s41586-022-04472-z)**Xi Wang, Chengxin Xiao, Heonjoon Park et al.*145 citations*
550. **[The mechanism of RNA capping by SARS-CoV-2 ↗](https://doi.org/10.1038/s41586-022-05185-z)**Gina J. Park, Adam Osinski, Genaro Hernandez et al.*145 citations*
551. **[What's next for AlphaFold and the AI protein-folding revolution ↗](https://doi.org/10.1038/d41586-022-00997-5)**Ewen Callaway*145 citations*
552. **[Wind dispersal of battery-free wireless devices ↗](https://doi.org/10.1038/s41586-021-04363-9)**Vikram Iyer, Hans Gaensbauer, Thomas L. Daniel et al.*145 citations*
553. **[Synthesis of chiral sulfinate esters by asymmetric condensation ↗](https://doi.org/10.1038/s41586-022-04524-4)**Xin Zhang, Esther Cai Xia Ang, Ziqi Yang et al.*144 citations*
554. **[A vaccine targeting resistant tumours by dual T cell plus NK cell attack ↗](https://doi.org/10.1038/s41586-022-04772-4)**Soumya Badrinath, Maxence O. Dellacherie, Aileen W. Li et al.*143 citations*
555. **[Atomic imaging of zeolite-confined single molecules by electron microscopy ↗](https://doi.org/10.1038/s41586-022-04876-x)**Boyuan Shen, Huiqiu Wang, Hao D. Xiong et al.*143 citations*
556. **[Dopamine subsystems that track internal states ↗](https://doi.org/10.1038/s41586-022-04954-0)**James C. R. Grove, Lindsay A. Gray, Naymalis La Santa Medina et al.*143 citations*
557. **[Neuropeptide regulation of non-redundant ILC2 responses at barrier surfaces ↗](https://doi.org/10.1038/s41586-022-05297-6)**Amy M. Tsou, Hiroshi Yano, Christopher N. Parkhurst et al.*143 citations*
558. **[The source of the Black Death in fourteenth-century central Eurasia ↗](https://doi.org/10.1038/s41586-022-04800-3)**Maria A. Spyrou, Lyazzat Musralina, Guido Alberto Gnecchi‐Ruscone et al.*143 citations*
559. **[Age of the oldest known Homo sapiens from eastern Africa ↗](https://doi.org/10.1038/s41586-021-04275-8)**Céline M. Vidal, Christine S. Lane, Asfawossen Asrat et al.*142 citations*
560. **[Behavioural and dopaminergic signatures of resilience ↗](https://doi.org/10.1038/s41586-022-05328-2)**Lindsay Willmore, Courtney Cameron, John Yang et al.*142 citations*
561. **[Engineering topological states in atom-based semiconductor quantum dots ↗](https://doi.org/10.1038/s41586-022-04706-0)**M. Kiczynski, Samuel Keith Gorman, Helen Geng et al.*142 citations*
562. **[Genetic instability from a single S phase after whole-genome duplication ↗](https://doi.org/10.1038/s41586-022-04578-4)**Simon Gemble, René Wardenaar, Kristina Keuper et al.*142 citations*
563. **[Mechanical integrated circuit materials ↗](https://doi.org/10.1038/s41586-022-05004-5)**Charles El Helou, Benjamin Großmann, Christopher E. Tabor et al.*142 citations*
564. **[Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4 ↗](https://doi.org/10.1038/s41586-022-04590-8)**Peng Xiao, Shengchao Guo, Xin Wen et al.*142 citations*
565. **[A kinase-cGAS cascade to synthesize a therapeutic STING activator ↗](https://doi.org/10.1038/s41586-022-04422-9)**John A. McIntosh, Zhijian Liu, Brian M. Andresen et al.*141 citations*
566. **[Free-standing homochiral 2D monolayers by exfoliation of molecular crystals ↗](https://doi.org/10.1038/s41586-022-04407-8)**Jinqiao Dong, Lingmei Liu, Chunxia Tan et al.*141 citations*
567. **[Glucose-driven TOR–FIE–PRC2 signalling controls plant development ↗](https://doi.org/10.1038/s41586-022-05171-5)**Ruiqiang Ye, Meiyue Wang, Hao Du et al.*141 citations*
568. **[Integrated multi-omic characterization of congenital heart disease ↗](https://doi.org/10.1038/s41586-022-04989-3)**Matthew C. Hill, Zachary A. Kadow, Hali Long et al.*141 citations*
569. **[Mitochondrial uncouplers induce proton leak by activating AAC and UCP1 ↗](https://doi.org/10.1038/s41586-022-04747-5)**Ambre M. Bertholet, Andrew M. Natale, Paola Bisignano et al.*141 citations*
570. **[Multifunctional biocatalyst for conjugate reduction and reductive amination ↗](https://doi.org/10.1038/s41586-022-04458-x)**Thomas W. Thorpe, James R. Marshall, Vanessa Harawa et al.*141 citations*
571. **[Nitrogen reduction by the Fe sites of synthetic Mo3S4Fe cubes ↗](https://doi.org/10.1038/s41586-022-04848-1)**Yasuhiro Ohki, Kenichiro Munakata, Yuto Matsuoka et al.*141 citations*
572. **[Structural insights into auxin recognition and efflux by Arabidopsis PIN1 ↗](https://doi.org/10.1038/s41586-022-05143-9)**Zhisen Yang, Jing Xia, Jingjing Hong et al.*141 citations*
573. **[Biosynthesis of selenium-containing small molecules in diverse microorganisms ↗](https://doi.org/10.1038/s41586-022-05174-2)**Chase M. Kayrouz, Jonathan Huang, Nicole Hauser et al.*140 citations*
574. **[Polarized blazar X-rays imply particle acceleration in shocks ↗](https://doi.org/10.1038/s41586-022-05338-0)**Ioannis Liodakis, Alan P. Marscher, I. Agudo et al.*140 citations*
575. **[Automated iterative Csp3–C bond formation ↗](https://doi.org/10.1038/s41586-022-04491-w)**Daniel J. Blair, Sriyankari Chitti, Melanie Trobe et al.*139 citations*
576. **[CLN3 is required for the clearance of glycerophosphodiesters from lysosomes ↗](https://doi.org/10.1038/s41586-022-05221-y)**Nouf N. Laqtom, Wentao Dong, Uche N. Medoh et al.*139 citations*
577. **[Electrocatalytic metal hydride generation using CPET mediators ↗](https://doi.org/10.1038/s41586-022-04874-z)**Subal Dey, Fabio Masero, Enzo Brack et al.*139 citations*
578. **[Non-redundant functions of group 2 innate lymphoid cells ↗](https://doi.org/10.1038/s41586-022-05395-5)**Katja J. Jarick, Patrycja M. Forster, Manuel O. Jakob et al.*139 citations*
579. **[Single-cell genomic variation induced by mutational processes in cancer ↗](https://doi.org/10.1038/s41586-022-05249-0)**Tyler Funnell, Ciara H. O’Flanagan, Marc J. Williams et al.*139 citations*
580. **[AAV-delivered suppressor tRNA overcomes a nonsense mutation in mice ↗](https://doi.org/10.1038/s41586-022-04533-3)**Jiaming Wang, Yue Zhang, Craig A. Mendonca et al.*138 citations*
581. **[Are ChatGPT and AlphaCode going to replace programmers? ↗](https://doi.org/10.1038/d41586-022-04383-z)**Davide Castelvecchi*138 citations*
582. **[Autonomous fuelled directional rotation about a covalent single bond ↗](https://doi.org/10.1038/s41586-022-04450-5)**Stefan Borsley, Elisabeth Kreidt, David A. Leigh et al.*138 citations*
583. **[Realizing the symmetry-protected Haldane phase in Fermi–Hubbard ladders ↗](https://doi.org/10.1038/s41586-022-04688-z)**Pimonpan Sompet, Sarah Hirthe, Dominik Bourgund et al.*138 citations*
584. **[Neuropathic pain caused by miswiring and abnormal end organ targeting ↗](https://doi.org/10.1038/s41586-022-04777-z)**Vijayan Gangadharan, Hongwei Zheng, Francisco José Taberner et al.*137 citations*
585. **[A photonic integrated continuous-travelling-wave parametric amplifier ↗](https://doi.org/10.1038/s41586-022-05329-1)**Johann Riemensberger, Nikolai Kuznetsov, Junqiu Liu et al.*136 citations*
586. **[Evolution of Earth’s tectonic carbon conveyor belt ↗](https://doi.org/10.1038/s41586-022-04420-x)**R. Dietmar Müller, Ben Mather, Adriana Dutkiewicz et al.*136 citations*
587. **[Free-space dissemination of time and frequency with 10−19 instability over 113 km ↗](https://doi.org/10.1038/s41586-022-05228-5)**Qi Shen, Jian-Yu Guan, Ji-Gang Ren et al.*136 citations*
588. **[Topological Chern vectors in three-dimensional photonic crystals ↗](https://doi.org/10.1038/s41586-022-05077-2)**Gui-Geng Liu, Zhen Liang Gao, Qiang Wang et al.*136 citations*
589. **[Plant receptor-like protein activation by a microbial glycoside hydrolase ↗](https://doi.org/10.1038/s41586-022-05214-x)**Yue Sun, Yan Wang, Xiaoxiao Zhang et al.*135 citations*
590. **[Regulation of liver subcellular architecture controls metabolic homeostasis ↗](https://doi.org/10.1038/s41586-022-04488-5)**Güneş Parlakgül, Ana Paula Arruda, Song Pang et al.*135 citations*
591. **[Cortical preparatory activity indexes learned motor memories ↗](https://doi.org/10.1038/s41586-021-04329-x)**Xulu Sun, Daniel J. O’Shea, Matthew D. Golub et al.*134 citations*
592. **[Enteric viruses replicate in salivary glands and infect through saliva ↗](https://doi.org/10.1038/s41586-022-04895-8)**Sourish Ghosh, Manish Kumar, Marianita Santiana et al.*134 citations*
593. **[Quantum state preparation and tomography of entangled mechanical resonators ↗](https://doi.org/10.1038/s41586-022-04500-y)**E. Alex Wollack, Agnetta Y. Cleland, Rachel G. Gruenke et al.*134 citations*
594. **[Social trauma engages lateral septum circuitry to occlude social reward ↗](https://doi.org/10.1038/s41586-022-05484-5)**Long Li, Romain Durand-de Cuttoli, Antonio Aubry et al.*134 citations*
595. **[Spatiotemporal dynamics of noradrenaline during learned behaviour ↗](https://doi.org/10.1038/s41586-022-04782-2)**Vincent Breton‐Provencher, Gabrielle T Drummond, Jiesi Feng et al.*134 citations*
596. **[Structural basis for the tethered peptide activation of adhesion GPCRs ↗](https://doi.org/10.1038/s41586-022-04619-y)**Yu-Qi Ping, Peng Xiao, Fan Yang et al.*134 citations*
597. **[The staggering death toll of drug-resistant bacteria ↗](https://doi.org/10.1038/d41586-022-00228-x)**Tosin Thompson*134 citations*
598. **[Ultra-narrow optical linewidths in rare-earth molecular crystals ↗](https://doi.org/10.1038/s41586-021-04316-2)**Diana Serrano, Senthil Kumar Kuppusamy, Benoı̂t Heinrich et al.*134 citations*
599. **[Cryo-EM structure of a type IV secretion system ↗](https://doi.org/10.1038/s41586-022-04859-y)**Kevin Macé, Abhinav Koyamangalath Vadakkepat, Adam Redzej et al.*132 citations*
600. **[Extreme heatwaves: surprising lessons from the record warmth ↗](https://doi.org/10.1038/d41586-022-02114-y)**Alexandra Witze*132 citations*

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