---
title: "Proceedings of the National Academy of Sciences 2014 — all"
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# Proceedings of the National Academy of Sciences 2014: all accepted papers

4,163 papers · page 6 of 42 · the most cited first · [← Proceedings of the National Academy of Sciences 2014](https://md.research.elamur.ai/free/en/venues/proceedings-of-the-national-academy-of-sciences/2014/)

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501. **[Notch signaling regulates cardiomyocyte proliferation during zebrafish heart regeneration ↗](https://doi.org/10.1073/pnas.1311705111)**Long Zhao, Asya L. Borikova, Raz Ben-Yair et al.*255 citations*
502. **[GSK3-like kinases positively modulate abscisic acid signaling through phosphorylating subgroup III SnRK2s in Arabidopsis ↗](https://doi.org/10.1073/pnas.1316717111)**Zhenying Cai, Jingjing Liu, Haijiao Wang et al.*254 citations*
503. **[In silico selection of therapeutic antibodies for development: Viscosity, clearance, and chemical stability ↗](https://doi.org/10.1073/pnas.1421779112)**Vikas Kumar Sharma, Thomas W. Patapoff, Bruce Kabakoff et al.*254 citations*
504. **[Critical slowing down as early warning for the onset of collapse in mutualistic communities ↗](https://doi.org/10.1073/pnas.1406326111)**Vasilis Dakos, Jordi Bascompte*253 citations*
505. **[Ethnic diversity deflates price bubbles ↗](https://doi.org/10.1073/pnas.1407301111)**Sheen S. Levine, Evan P. Apfelbaum, Mark M. Bernard et al.*252 citations*
506. **[Generation of multiciliated cells in functional airway epithelia from human induced pluripotent stem cells ↗](https://doi.org/10.1073/pnas.1403470111)**Amy L. Firth, Carl Dargitz, Susan J. Qualls et al.*252 citations*
507. **[Life cycle air quality impacts of conventional and alternative light-duty transportation in the United States ↗](https://doi.org/10.1073/pnas.1406853111)**Christopher W. Tessum, Jason Hill, Julian D. Marshall*252 citations*
508. **[Microscopic insights into the protein-stabilizing effect of trimethylamine N-oxide (TMAO) ↗](https://doi.org/10.1073/pnas.1403224111)**Jianqiang Ma, Ileana M. Pazos, Feng Gai*252 citations*
509. **[Sphericity and symmetry breaking in the formation of Frank–Kasper phases from one component materials ↗](https://doi.org/10.1073/pnas.1408678111)**Sangwoo Lee, Chris Leighton, Frank S. Bates*252 citations*
510. **[Deep, noninvasive imaging and surgical guidance of submillimeter tumors using targeted M13-stabilized single-walled carbon nanotubes ↗](https://doi.org/10.1073/pnas.1400821111)**Debadyuti Ghosh, Alexander F. Bagley, Young Jeong Na et al.*251 citations*
511. **[Fallout plume of submerged oil from Deepwater Horizon ↗](https://doi.org/10.1073/pnas.1414873111)**David L. Valentine, G. Burch Fisher, Sarah C. Bagby et al.*251 citations*
512. **[Public awareness, concerns, and priorities about anthropogenic impacts on marine environments ↗](https://doi.org/10.1073/pnas.1417344111)**Stefan Gelcich, Paul J. Buckley, John K. Pinnegar et al.*251 citations*
513. **[Exploring exoplanet populations with NASA’s Kepler Mission ↗](https://doi.org/10.1073/pnas.1304196111)**Natalie M. Batalha*250 citations*
514. **[Nonlytic viral spread enhanced by autophagy components ↗](https://doi.org/10.1073/pnas.1401437111)**Sara W. Bird, Nathaniel D. Maynard, Markus W. Covert et al.*250 citations*
515. **[Overexpression of a DENND1A isoform produces a polycystic ovary syndrome theca phenotype ↗](https://doi.org/10.1073/pnas.1400574111)**Jan M. McAllister, Bhavi P. Modi, Bruce A. Miller et al.*250 citations*
516. **[Physical activity when young provides lifelong benefits to cortical bone size and strength in men ↗](https://doi.org/10.1073/pnas.1321605111)**Stuart J. Warden, Sara M. Mantila Roosa, Mariana E. Kersh et al.*250 citations*
517. **[Unspeciated organic emissions from combustion sources and their influence on the secondary organic aerosol budget in the United States ↗](https://doi.org/10.1073/pnas.1323740111)**Shantanu H. Jathar, T. D. Gordon, Christopher J. Hennigan et al.*250 citations*
518. **[25-Hydroxycholesterol acts as an amplifier of inflammatory signaling ↗](https://doi.org/10.1073/pnas.1404271111)**Elizabeth S. Gold, Alan H. Diercks, Irina Podolsky et al.*249 citations*
519. **[Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers ↗](https://doi.org/10.1073/pnas.1401724111)**Kemal Marc Akat, D’Vesharronne Moore-McGriff, Pavel S Morozov et al.*249 citations*
520. **[Dynamic architecture of a protein kinase ↗](https://doi.org/10.1073/pnas.1418402111)**Christopher L. McClendon, Alexandr P. Kornev, Michael K. Gilson et al.*249 citations*
521. **[Long-term effects of marijuana use on the brain ↗](https://doi.org/10.1073/pnas.1415297111)**Francesca Mapua Filbey, Sina Aslan, Vince D. Calhoun et al.*249 citations*
522. **[Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity ↗](https://doi.org/10.1073/pnas.1406974111)**Zahra Sabouri, Peter Schofield, Keisuke Horikawa et al.*249 citations*
523. **[CD28 and CD3 have complementary roles in T-cell traction forces ↗](https://doi.org/10.1073/pnas.1315606111)**Keenan T. Bashour, Alexander A. Gondarenko, Haoqian Chen et al.*248 citations*
524. **[Dynamic regulation of eve stripe 2 expression reveals transcriptional bursts in living Drosophila embryos ↗](https://doi.org/10.1073/pnas.1410022111)**Jacques P. Bothma, Hernán G. García, Emilia Esposito et al.*248 citations*
525. **[Microvesicles containing miRNAs promote muscle cell death in cancer cachexia via TLR7 ↗](https://doi.org/10.1073/pnas.1402714111)**Wei A. He, Federica Calore, Priya Londhe et al.*248 citations*
526. **[Oxysterols are agonist ligands of RORγt and drive Th17 cell differentiation ↗](https://doi.org/10.1073/pnas.1322807111)**Pejman Soroosh, Jiejun Wu, Xiaohua Xue et al.*248 citations*
527. **[Responses to social and environmental stress are attenuated by strong male bonds in wild macaques ↗](https://doi.org/10.1073/pnas.1411450111)**Christopher Young, Bonaventura Majolo, Michael Heistermann et al.*248 citations*
528. **[Spatial constraints control cell proliferation in tissues ↗](https://doi.org/10.1073/pnas.1323016111)**Sebastian J. Streichan, Christian R. Hoerner, Tatjana Schneidt et al.*248 citations*
529. **[A tick-borne segmented RNA virus contains genome segments derived from unsegmented viral ancestors ↗](https://doi.org/10.1073/pnas.1324194111)**Xin-Cheng Qin, Mǎng Shī, Jun-Hua Tian et al.*247 citations*
530. **[Application of desorption electrospray ionization mass spectrometry imaging in breast cancer margin analysis ↗](https://doi.org/10.1073/pnas.1408129111)**David Calligaris, Diana L. Caragacianu, Xiaohui Liu et al.*247 citations*
531. **[Control of vacuolar dynamics and regulation of stomatal aperture by tonoplast potassium uptake ↗](https://doi.org/10.1073/pnas.1320421111)**Zaida Andrés, Javier Pérez-Hormaeche, Eduardo O. Leidi et al.*247 citations*
532. **[Functional type 2 photosynthetic reaction centers found in the rare bacterial phylum Gemmatimonadetes ↗](https://doi.org/10.1073/pnas.1400295111)**Yonghui Zeng, Fuying Feng, Hana Medová et al.*247 citations*
533. **[Patterns of coding variation in the complete exomes of three Neandertals ↗](https://doi.org/10.1073/pnas.1405138111)**Sergi Castellano, Genı́s Parra, Federico Sánchez‐Quinto et al.*247 citations*
534. **[Intracellular metabolite levels shape sulfur isotope fractionation during microbial sulfate respiration ↗](https://doi.org/10.1073/pnas.1407502111)**Boswell A. Wing, Itay Halevy*246 citations*
535. **[Network measures predict neuropsychological outcome after brain injury ↗](https://doi.org/10.1073/pnas.1322173111)**David E. Warren, Jonathan D. Power, Joel Bruss et al.*246 citations*
536. **[Observational determination of albedo decrease caused by vanishing Arctic sea ice ↗](https://doi.org/10.1073/pnas.1318201111)**Kristina Pistone, Ian Eisenman, V. Ramanathan*246 citations*
537. **[(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium ↗](https://doi.org/10.1073/pnas.1414221111)**Marı́a Belén Jiménez-Dı́az, Daniel Ebert, Yandira G. Salinas et al.*245 citations*
538. **[Anaerobic methane oxidation coupled to denitrification is the dominant methane sink in a deep lake ↗](https://doi.org/10.1073/pnas.1411617111)**Jörg Stefan Deutzmann, Peter Stief, Josephin Brandes et al.*245 citations*
539. **[Detouring of cisplatin to access mitochondrial genome for overcoming resistance ↗](https://doi.org/10.1073/pnas.1405244111)**Sean Marrache, Rakesh Pathak, Shanta Dhar*245 citations*
540. **[Quenched disorder and vestigial nematicity in the pseudogap regime of the cuprates ↗](https://doi.org/10.1073/pnas.1406019111)**Laimei Nie, Gilles Tarjus, Steven Allan Kivelson*245 citations*
541. **[Remodeling of intermediate metabolism in the diatom Phaeodactylum tricornutum under nitrogen stress ↗](https://doi.org/10.1073/pnas.1419818112)**Orly Levitan, Jorge Dinamarca, Ehud Zelzion et al.*245 citations*
542. **[Single-molecule spectroscopy reveals polymer effects of disordered proteins in crowded environments ↗](https://doi.org/10.1073/pnas.1322611111)**Andrea Soranno, Iwo König, Madeleine B. Borgia et al.*245 citations*
543. **[Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo ↗](https://doi.org/10.1073/pnas.1402723111)**Mark E. Juhas, George C. Engelmayr, Andrew N. Fontanella et al.*244 citations*
544. **[Lag in maturation of the brain’s intrinsic functional architecture in attention-deficit/hyperactivity disorder ↗](https://doi.org/10.1073/pnas.1407787111)**Chandra Sripada, Daniel A. Kessler, Mike Angstadt*244 citations*
545. **[Molecular basis for the recognition of methylated adenines in RNA by the eukaryotic YTH domain ↗](https://doi.org/10.1073/pnas.1412742111)**Shukun Luo, Liang Tong*244 citations*
546. **[Nitrate foraging by Arabidopsis roots is mediated by the transcription factor TCP20 through the systemic signaling pathway ↗](https://doi.org/10.1073/pnas.1411375111)**Peizhu Guan, Rongchen Wang, Philippe Nacry et al.*244 citations*
547. **[Trajectories of the ribosome as a Brownian nanomachine ↗](https://doi.org/10.1073/pnas.1419276111)**Ali Dashti, Peter Schwander, Robert Ezra Langlois et al.*243 citations*
548. **[Effects of biological explanations for mental disorders on clinicians’ empathy ↗](https://doi.org/10.1073/pnas.1414058111)**Matthew S. Lebowitz, Woo‐kyoung Ahn*242 citations*
549. **[Fluvial network organization imprints on microbial co-occurrence networks ↗](https://doi.org/10.1073/pnas.1411723111)**Stefanie Widder A, Katharina Besemer, Gabriel Andreas Singer et al.*242 citations*
550. **[Identification and characterization of the constituent human serum antibodies elicited by vaccination ↗](https://doi.org/10.1073/pnas.1317793111)**Jason J. Lavinder, Yariv Wine, Claudia Giesecke‐Thiel et al.*242 citations*
551. **[Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia ↗](https://doi.org/10.1073/pnas.1313093111)**Shashwath A. Meda, Gualberto Ruaño, Andreas Windemuth et al.*242 citations*
552. **[Predicting hybrid performance in rice using genomic best linear unbiased prediction ↗](https://doi.org/10.1073/pnas.1413750111)**Shizhong Xu, Dan Yan Zhu, Qifa Zhang*242 citations*
553. **[Small RNA combination therapy for lung cancer ↗](https://doi.org/10.1073/pnas.1412686111)**Wen Xue, James E. Dahlman, Tuomas Tammela et al.*242 citations*
554. **[Functional recovery with recombinant human IGF1 treatment in a mouse model of Rett Syndrome ↗](https://doi.org/10.1073/pnas.1311685111)**Jorge E. Castro, Rodrigo I. Garcia, Showming Kwok et al.*241 citations*
555. **[Adaptive optoelectronic camouflage systems with designs inspired by cephalopod skins ↗](https://doi.org/10.1073/pnas.1410494111)**Cunjiang Yu, Yuhang Li, Xun Zhang et al.*240 citations*
556. **[Epitaxial superlattices with titanium nitride as a plasmonic component for optical hyperbolic metamaterials ↗](https://doi.org/10.1073/pnas.1319446111)**Gururaj V. Naik, Bivas Saha, Jing Liu et al.*240 citations*
557. **[In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C ↗](https://doi.org/10.1073/pnas.1404639111)**John C. Hunter, Deepak Gurbani, Scott B. Ficarro et al.*240 citations*
558. **[MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus ↗](https://doi.org/10.1073/pnas.1407843111)**Bhavik P. Shah, Linh Vong, David P. Olson et al.*240 citations*
559. **[Patterns of genome evolution that have accompanied host adaptation in Salmonella ↗](https://doi.org/10.1073/pnas.1416707112)**Gemma C. Langridge, Maria C. Fookes, Thomas R. Connor et al.*240 citations*
560. **[Involvement of the host DNA-repair enzyme TDP2 in formation of the covalently closed circular DNA persistence reservoir of hepatitis B viruses ↗](https://doi.org/10.1073/pnas.1409986111)**Christian Königer, Ida Wingert, Moritz Marsmann et al.*239 citations*
561. **[Population of sensory neurons essential for asthmatic hyperreactivity of inflamed airways ↗](https://doi.org/10.1073/pnas.1411032111)**Dimitri Tränkner, Nadeau Hahne, Ken Sugino et al.*239 citations*
562. **[Activating mutations in STIM1 and ORAI1 cause overlapping syndromes of tubular myopathy and congenital miosis ↗](https://doi.org/10.1073/pnas.1312520111)**Vasyl Nesin, Graham B. Wiley, Maria Kousi et al.*238 citations*
563. **[Direct phase-sensitive identification of a d -form factor density wave in underdoped cuprates ↗](https://doi.org/10.1073/pnas.1406297111)**Kazuhiro A. Fujita, Mohammad H. Hamidian, Stephen D. Edkins et al.*238 citations*
564. **[Notes on the role of dynamic DNA methylation in mammalian development ↗](https://doi.org/10.1073/pnas.1415301111)**Timothy H. Bestor, John R. Edwards, Mathieu Boulard*238 citations*
565. **[Rapid short-term cooling following the Chicxulub impact at the Cretaceous–Paleogene boundary ↗](https://doi.org/10.1073/pnas.1319253111)**Johan Vellekoop, Appy Sluijs, Jan Smit et al.*238 citations*
566. **[Blood–spinal cord barrier disruption contributes to early motor-neuron degeneration in ALS-model mice ↗](https://doi.org/10.1073/pnas.1401595111)**Ethan A. Winkler, Jesse D. Sengillo, Abhay P. Sagare et al.*237 citations*
567. **[Mountain runoff vulnerability to increased evapotranspiration with vegetation expansion ↗](https://doi.org/10.1073/pnas.1319316111)**Michael L. Goulden, Roger C. Bales*237 citations*
568. **[OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin ↗](https://doi.org/10.1073/pnas.1314939111)**Ligong Chen, Yan Shu, Xiaomin Liang et al.*237 citations*
569. **[Bioengineering T cells to target carbohydrate to treat opportunistic fungal infection ↗](https://doi.org/10.1073/pnas.1312789111)**Pappanaicken R. Kumaresan, Pallavi R. Manuri, Nathaniel D. Albert et al.*236 citations*
570. **[Direct conversion of plant biomass to ethanol by engineered Caldicellulosiruptor bescii ↗](https://doi.org/10.1073/pnas.1402210111)**Daehwan Chung, Minseok Cha, Adam M. Guss et al.*236 citations*
571. **[SUMOylation at K340 inhibits tau degradation through deregulating its phosphorylation and ubiquitination ↗](https://doi.org/10.1073/pnas.1417548111)**Hongbin Luo, Yiyuan Xia, Xiji Shu et al.*236 citations*
572. **[Human and Helicobacter pylori coevolution shapes the risk of gastric disease ↗](https://doi.org/10.1073/pnas.1318093111)**Nuri M. Kodaman, Alvaro J. Pazos, Barbara Schneider et al.*235 citations*
573. **[Nonflammable perfluoropolyether-based electrolytes for lithium batteries ↗](https://doi.org/10.1073/pnas.1314615111)**Dominica H. C. Wong, Jacob L. Thelen, Yanbao Fu et al.*235 citations*
574. **[Epitaxial growth of large-gap quantum spin Hall insulator on semiconductor surface ↗](https://doi.org/10.1073/pnas.1409701111)**Miao Zhou, Wenmei Ming, Zheng Liu et al.*234 citations*
575. **[Global evaluation of biofuel potential from microalgae ↗](https://doi.org/10.1073/pnas.1321652111)**Jeffrey Moody, Christopher M. McGinty, Jason C. Quinn*234 citations*
576. **[Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans ↗](https://doi.org/10.1073/pnas.1414070111)**Ali H. Ellebedy, Florian Krammer, Guimei Li et al.*234 citations*
577. **[Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA ↗](https://doi.org/10.1073/pnas.1409328111)**Boris Rebolledo‐Jaramillo, Marcia Shu‐Wei Su, Nicholas Stoler et al.*234 citations*
578. **[Role of pyruvate kinase M2 in transcriptional regulation leading to epithelial–mesenchymal transition ↗](https://doi.org/10.1073/pnas.1407717111)**Atsushi Hamabe, Masamitsu Konno, Nobuhiro Tanuma et al.*234 citations*
579. **[Dicer-like 3 produces transposable element-associated 24-nt siRNAs that control agricultural traits in rice ↗](https://doi.org/10.1073/pnas.1318131111)**Liya Wei, Lianfeng Gu, Xianwei Song et al.*233 citations*
580. **[Discontinuity in the responses of ecosystem processes and multifunctionality to altered soil community composition ↗](https://doi.org/10.1073/pnas.1413707111)**Mark A. Bradford, Stephen Andrew Wood, Richard D. Bardgett et al.*233 citations*
581. **[Expression and prognostic impact of lncRNAs in acute myeloid leukemia ↗](https://doi.org/10.1073/pnas.1422050112)**Ramiro Garzon, Stefano Volinia, Dimitrios Papaioannou et al.*233 citations*
582. **[Single bacterial strain capable of significant contribution to carbon cycling in the surface ocean ↗](https://doi.org/10.1073/pnas.1401887111)**Byron E. Pedler, Lihini I. Aluwihare, Farooq Azam*233 citations*
583. **[The Irish potato famine pathogen Phytophthora infestans originated in central Mexico rather than the Andes ↗](https://doi.org/10.1073/pnas.1401884111)**Erica M. Goss, Javier F. Tabima, David E. L. Cooke et al.*233 citations*
584. **[Highly sensitive detection of nanoparticles with a self-referenced and self-heterodyned whispering-gallery Raman microlaser ↗](https://doi.org/10.1073/pnas.1408283111)**Şahin Kaya Özdemir, Jian‐Gang Zhu, Yang Xu et al.*232 citations*
585. **[Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution ↗](https://doi.org/10.1073/pnas.1402074111)**Xian-Chun Tang, Sudhakar Agnihothram, Yongjun Jiao et al.*232 citations*
586. **[Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses ↗](https://doi.org/10.1073/pnas.1323920111)**Erinn S. Gideons, Ege T. Kavalali, Lisa M. Monteggia*232 citations*
587. **[Quantification of HIV-1 latency reversal in resting CD4 + T cells from patients on suppressive antiretroviral therapy ↗](https://doi.org/10.1073/pnas.1402873111)**Anthony Richard Cillo, Michele D. Sobolewski, Ronald J. Bosch et al.*232 citations*
588. **[Evolution of microbial markets ↗](https://doi.org/10.1073/pnas.1315980111)**Gijsbert D. A. Werner, Joan E. Strassmann, Aniek B. F. Ivens et al.*231 citations*
589. **[GroEL from the endosymbiont Buchnera aphidicola betrays the aphid by triggering plant defense ↗](https://doi.org/10.1073/pnas.1407687111)**Ritu Chaudhary, Hagop S. Atamian, Zhouxin Shen et al.*231 citations*
590. **[Local genomic adaptation of coral reef-associated microbiomes to gradients of natural variability and anthropogenic stressors ↗](https://doi.org/10.1073/pnas.1403319111)**Linda Wegley Kelly, Gareth J. Williams, Katie L. Barott et al.*231 citations*
591. **[Microbial biosynthesis of medium-chain 1-alkenes by a nonheme iron oxidase ↗](https://doi.org/10.1073/pnas.1419701112)**Zhe Rui, Xin Li, Xuejun Zhu et al.*231 citations*
592. **[Modeling first impressions from highly variable facial images ↗](https://doi.org/10.1073/pnas.1409860111)**Richard J. W. Vernon, Clare A. M. Sutherland, Andrew W. Young et al.*231 citations*
593. **[Molecular basis of a shattering resistance boosting global dissemination of soybean ↗](https://doi.org/10.1073/pnas.1417282111)**Hideyuki Funatsuki, Masaya Suzuki, Aya Hirose et al.*231 citations*
594. **[NODULE INCEPTION creates a long-distance negative feedback loop involved in homeostatic regulation of nodule organ production ↗](https://doi.org/10.1073/pnas.1412716111)**Takashi Soyano, Hideki Hirakawa, Shusei Sato et al.*231 citations*
595. **[O-GlcNAcylation regulates EZH2 protein stability and function ↗](https://doi.org/10.1073/pnas.1323226111)**Chi-Shuen Chu, Pei-Wen Lo, Yi-Hsien Yeh et al.*231 citations*
596. **[A common neural code for similar conscious experiences in different individuals ↗](https://doi.org/10.1073/pnas.1407007111)**Lorina Naçi, Rhodri Cusack, Mimma Anello et al.*230 citations*
597. **[Decreased dopamine brain reactivity in marijuana abusers is associated with negative emotionality and addiction severity ↗](https://doi.org/10.1073/pnas.1411228111)**Nora D. Volkow, Gene‐Jack Wang, Frank Telang et al.*230 citations*
598. **[Direct activation of RIP3/MLKL-dependent necrosis by herpes simplex virus 1 (HSV-1) protein ICP6 triggers host antiviral defense ↗](https://doi.org/10.1073/pnas.1412767111)**Xing Wang, Yun Li, Shan Liu et al.*230 citations*
599. **[Scaling laws governing stochastic growth and division of single bacterial cells ↗](https://doi.org/10.1073/pnas.1403232111)**Srividya Iyer‐Biswas, Charles W. Wright, Jonathan T. Henry et al.*230 citations*
600. **[Isotopically nonstationary 13 C flux analysis of changes in Arabidopsis thaliana leaf metabolism due to high light acclimation ↗](https://doi.org/10.1073/pnas.1319485111)**Fangfang Ma, Lara J. Jazmin, Jamey D. Young et al.*229 citations*

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