---
title: "Science 2022 — all accepted papers — the most cited first"
description: "All 2,047 papers of Science 2022 · page 1 of 21, the most cited first; those with our summary link to it."
canonical: "https://research.elamur.ai/free/en/venues/science/2022/papers/"
---
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# Science 2022: all accepted papers

2,047 papers · page 1 of 21 · the most cited first · [← Science 2022](https://md.research.elamur.ai/free/en/venues/science/2022/)

**1** [2](https://md.research.elamur.ai/free/en/venues/science/2022/papers/page/2/) … [10](https://md.research.elamur.ai/free/en/venues/science/2022/papers/page/10/) … [21](https://md.research.elamur.ai/free/en/venues/science/2022/papers/page/21/) [next →](https://md.research.elamur.ai/free/en/venues/science/2022/papers/page/2/)

1. **[Copper induces cell death by targeting lipoylated TCA cycle proteins ↗](https://doi.org/10.1126/science.abf0529)**Peter Tsvetkov, Shannon Coy, Boryana Petrova et al.*4,849 citations*
2. **[The complete sequence of a human genome ↗](https://doi.org/10.1126/science.abj6987)**Sergey Nurk, Sergey Koren, Arang Rhie et al.*3,060 citations*
3. **[Per- and polyfluoroalkyl substances in the environment ↗](https://doi.org/10.1126/science.abg9065)**Marina G. Evich, Mary J. B. Davis, James P. McCord et al.*2,106 citations*
4. **[Robust deep learning–based protein sequence design using ProteinMPNN ↗](https://doi.org/10.1126/science.add2187)**Justas Dauparas, Ivan V. Anishchenko, Nathaniel R. Bennett et al.*2,051 citations*
5. **[Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis ↗](https://doi.org/10.1126/science.abj8222)**Kjetil Bjørnevik, Marianna Cortese, Brian C. Healy et al.*2,027 citations*
6. **[Exceeding 1.5°C global warming could trigger multiple climate tipping points ↗](https://doi.org/10.1126/science.abn7950)**David I. Armstrong McKay, Arie Staal, Jesse F. Abrams et al.*1,915 citations*
7. **[Inactive (PbI 2 ) 2 RbCl stabilizes perovskite films for efficient solar cells ↗](https://doi.org/10.1126/science.abp8873)**Yang Zhao, Fei Ma, Zihan Qu et al.*1,445 citations*
8. **[Grassland soil carbon sequestration: Current understanding, challenges, and solutions ↗](https://doi.org/10.1126/science.abo2380)**Yongfei Bai, M. Francesca Cotrufo*1,356 citations*
9. **[CAR T cells produced in vivo to treat cardiac injury ↗](https://doi.org/10.1126/science.abm0594)**Joel G. Rurik, István Tombácz, Amir Yadegari et al.*1,353 citations*
10. **[Conformal quantum dot–SnO 2 layers as electron transporters for efficient perovskite solar cells ↗](https://doi.org/10.1126/science.abh1885)**Minjin Kim, Jaeki Jeong, Haizhou Lu et al.*1,346 citations*
11. **[Early detection of cancer ↗](https://doi.org/10.1126/science.aay9040)**David L. Crosby, Sangeeta N. Bhatia, Kevin Michael Brindle et al.*1,333 citations*
12. **[Cross-tissue immune cell analysis reveals tissue-specific features in humans ↗](https://doi.org/10.1126/science.abl5197)**Cecilia Domínguez Conde, Chuan Xu, Lorna B. Jarvis et al.*1,159 citations*
13. **[Tertiary lymphoid structures in cancer ↗](https://doi.org/10.1126/science.abf9419)**Ton N. Schumacher, Daniela S. Thommen*1,142 citations*
14. **[Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial ↗](https://doi.org/10.1126/science.abm3425)**Peter B. Gilbert, David C. Montefiori, Adrian B. McDermott et al.*1,135 citations*
15. **[High-entropy nanoparticles: Synthesis-structure-property relationships and data-driven discovery ↗](https://doi.org/10.1126/science.abn3103)**Yonggang Yao, Qi Dong, Alexandra H. Brozena et al.*1,071 citations*
16. **[The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans ↗](https://doi.org/10.1126/science.abl4896)**Robert C. Jones, Jim Karkanias, Mark A. Krasnow et al.*1,044 citations*
17. **[Organometallic-functionalized interfaces for highly efficient inverted perovskite solar cells ↗](https://doi.org/10.1126/science.abm8566)**Zhen Li, Bo Li, Xin Wu et al.*1,043 citations*
18. **[Increased risk of SARS-CoV-2 reinfection associated with emergence of Omicron in South Africa ↗](https://doi.org/10.1126/science.abn4947)**Juliet R.C. Pulliam, Cari van Schalkwyk, Nevashan Govender et al.*1,032 citations*
19. **[Competition-level code generation with AlphaCode](https://md.research.elamur.ai/free/en/papers/li-2022-competition-level-code-generation-alphacode/)**Yujia Li, David Choi, Junyoung Chung et al.*1,016 citations · our summary*
20. **[Self-assembled monolayers direct a LiF-rich interphase toward long-life lithium metal batteries ↗](https://doi.org/10.1126/science.abn1818)**Yujing Liu, Xinyong Tao, Yao Wang et al.*962 citations*
21. **[Constructing heterojunctions by surface sulfidation for efficient inverted perovskite solar cells ↗](https://doi.org/10.1126/science.abl5676)**Xiaodong Li, Wenxiao Zhang, Xuemin Guo et al.*907 citations*
22. **[Damp heat–stable perovskite solar cells with tailored-dimensionality 2D/3D heterojunctions ↗](https://doi.org/10.1126/science.abm5784)**Randi Azmi, Esma Ugur, Akmaral Seitkhan et al.*855 citations*
23. **[Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly ↗](https://doi.org/10.1126/science.abk2432)**Hongjie Li, Jasper Janssens, Maxime De Waegeneer et al.*837 citations*
24. **[The biodiversity and ecosystem service contributions and trade-offs of forest restoration approaches ↗](https://doi.org/10.1126/science.abl4649)**Fangyuan Hua, Leendert Adrian Bruijnzeel, Paula Meli et al.*806 citations*
25. **[Designing better electrolytes ↗](https://doi.org/10.1126/science.abq3750)**Ying Shirley Meng, Venkat N. Srinivasan, Kang Xu*751 citations*
26. **[The immunology and immunopathology of COVID-19 ↗](https://doi.org/10.1126/science.abm8108)**Miriam Mérad, Catherine A. Blish, Federica Sallusto et al.*751 citations*
27. **[Machine learning–enabled high-entropy alloy discovery ↗](https://doi.org/10.1126/science.abo4940)**Ziyuan Rao, Po‐Yen Tung, Ruiwen Xie et al.*745 citations*
28. **[High figure-of-merit and power generation in high-entropy GeTe-based thermoelectrics ↗](https://doi.org/10.1126/science.abq5815)**Binbin Jiang, Wu Wang, Shixuan Liu et al.*729 citations*
29. **[Soil microbiota as game-changers in restoration of degraded lands ↗](https://doi.org/10.1126/science.abe0725)**Oksana Coban, Gerlinde B. De Deyn, Martine J. van der Ploeg*713 citations*
30. **[Memristive technologies for data storage, computation, encryption, and radio-frequency communication ↗](https://doi.org/10.1126/science.abj9979)**Mario Lanza, Abu Sebastian, Wei Dong Lu et al.*708 citations*
31. **[Single-cell eQTL mapping identifies cell type–specific genetic control of autoimmune disease ↗](https://doi.org/10.1126/science.abf3041)**Seyhan Yazar, José Alquicira-Hernández, Kristof Wing et al.*656 citations*
32. **[Microbiota and maintenance of skin barrier function ↗](https://doi.org/10.1126/science.abo0693)**Tamia A. Harris-Tryon, Elizabeth A. Grice*651 citations*
33. **[Mixed plastics waste valorization through tandem chemical oxidation and biological funneling ↗](https://doi.org/10.1126/science.abo4626)**Kevin P. Sullivan, Allison Z. Werner, Kelsey J. Ramirez et al.*635 citations*
34. **[SARS-CoV-2 Omicron variant: Antibody evasion and cryo-EM structure of spike protein–ACE2 complex ↗](https://doi.org/10.1126/science.abn7760)**Dhiraj Mannar, James W. Saville, Xing Quan Zhu et al.*628 citations*
35. **[Chiral emission from resonant metasurfaces ↗](https://doi.org/10.1126/science.abq7870)**Xudong Zhang, Yilin Liu, Jiecai Han et al.*623 citations*
36. **[Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics ↗](https://doi.org/10.1126/science.abj7564)**Yuanwen Jiang, Zhitao Zhang, Yi-Xuan Wang et al.*617 citations*
37. **[Complete genomic and epigenetic maps of human centromeres ↗](https://doi.org/10.1126/science.abl4178)**Nicolas Altemose, Glennis A. Logsdon, Andrey V. Bzikadze et al.*601 citations*
38. **[Bioadhesive ultrasound for long-term continuous imaging of diverse organs ↗](https://doi.org/10.1126/science.abo2542)**Chonghe Wang, Xiaoyu Chen, Liu Wang et al.*599 citations*
39. **[Ultrahard magnetism from mixed-valence dilanthanide complexes with metal-metal bonding ↗](https://doi.org/10.1126/science.abl5470)**Colin A. Gould, K. Randall McClain, Daniel Reta et al.*596 citations*
40. **[Disentangling the numbers behind agriculture-driven tropical deforestation ↗](https://doi.org/10.1126/science.abm9267)**Florence Pendrill, Toby Alan Gardner, Patrick Meyfroidt et al.*564 citations*
41. **[Deterministic fabrication of 3D/2D perovskite bilayer stacks for durable and efficient solar cells ↗](https://doi.org/10.1126/science.abq7652)**Siraj Sidhik, Yafei Wang, Michael C. De Siena et al.*563 citations*
42. **[High-entropy mechanism to boost ionic conductivity ↗](https://doi.org/10.1126/science.abq1346)**Yan Zeng, Bin Ouyang, Jue Liu et al.*558 citations*
43. **[OpenCell: Endogenous tagging for the cartography of human cellular organization ↗](https://doi.org/10.1126/science.abi6983)**Nathan H. Cho, Keith C. Cheveralls, Andreas‐David Brunner et al.*557 citations*
44. **[Rethinking the A cation in halide perovskites ↗](https://doi.org/10.1126/science.abj1186)**Jin‐Wook Lee, Shaun Wee Kiat Tan, Sang Il Seok et al.*557 citations*
45. **[Cryo-EM structures of amyloid-β 42 filaments from human brains ↗](https://doi.org/10.1126/science.abm7285)**Yang Yang, Diana Arseni, Wenjuan Zhang et al.*549 citations*
46. **[Molecular basis of astrocyte diversity and morphology across the CNS in health and disease ↗](https://doi.org/10.1126/science.adc9020)**Fumito Endo, Atsushi Kasai, Joselyn S. Soto et al.*547 citations*
47. **[Big-data approaches lead to an increased understanding of the ecology of animal movement ↗](https://doi.org/10.1126/science.abg1780)**Ran Nathan, Christopher T. Monk, Robert Arlinghaus et al.*545 citations*
48. **[Exceptional fracture toughness of CrCoNi-based medium- and high-entropy alloys at 20 kelvin ↗](https://doi.org/10.1126/science.abp8070)**Dong Liu, Qin Yu, Saurabh Kabra et al.*543 citations*
49. **[Current global efforts are insufficient to limit warming to 1.5°C ↗](https://doi.org/10.1126/science.abo3378)**H. Damon Matthews, Seth Wynes*536 citations*
50. **[Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement ↗](https://doi.org/10.1126/science.abn8652)**Matthew McCallum, Nadine Czudnochowski, Laura E. Rosen et al.*534 citations*
51. **[Copper-induced cell death ↗](https://doi.org/10.1126/science.abo3959)**Martha A. Kahlson, Scott J. Dixon*521 citations*
52. **[Flexible thermoelectrics based on ductile semiconductors ↗](https://doi.org/10.1126/science.abq0682)**Qingyu Yang, Shiqi Yang, Pengfei Qiu et al.*518 citations*
53. **[Single-cell RNA-seq reveals cell type–specific molecular and genetic associations to lupus ↗](https://doi.org/10.1126/science.abf1970)**Richard K. Perez, M. Grace Gordon, Meena Subramaniam et al.*513 citations*
54. **[Quantum advantage in learning from experiments ↗](https://doi.org/10.1126/science.abn7293)**Hsin-Yuan Huang, Michael Broughton, Jordan S. Cotler et al.*511 citations*
55. **[Deep-learning seismology ↗](https://doi.org/10.1126/science.abm4470)**S. Mostafa Mousavi, Gregory C. Beroza*506 citations*
56. **[Covalent organic framework–based porous ionomers for high-performance fuel cells ↗](https://doi.org/10.1126/science.abm6304)**Qingnuan Zhang, Shuda Dong, Pengpeng Shao et al.*505 citations*
57. **[Dynamics of CTCF- and cohesin-mediated chromatin looping revealed by live-cell imaging ↗](https://doi.org/10.1126/science.abn6583)**Michele Gabriele, Hugo B. Brandão, Simon Grosse‐Holz et al.*501 citations*
58. **[Tissue geometry drives deterministic organoid patterning ↗](https://doi.org/10.1126/science.aaw9021)**Nikolche Gjorevski, Mikhail Nikolaev, Tobin E. Brown et al.*499 citations*
59. **[Three-dimensional direct lithography of stable perovskite nanocrystals in glass ↗](https://doi.org/10.1126/science.abj2691)**Ke Sun, Dezhi Tan, Xinyuan Fang et al.*498 citations*
60. **[High-resolution mapping of losses and gains of Earth’s tidal wetlands ↗](https://doi.org/10.1126/science.abm9583)**Nicholas Murray, Thomas A. Worthington, Peter Bunting et al.*489 citations*
61. **[High-precision measurement of the W boson mass with the CDF II detector ↗](https://doi.org/10.1126/science.abk1781)**T. Aaltonen, S. Amerio, D. Amidei et al.*488 citations*
62. **[Capturing the swelling of solid-electrolyte interphase in lithium metal batteries ↗](https://doi.org/10.1126/science.abi8703)**Zewen Zhang, Yuzhang Li, Rong Xu et al.*486 citations*
63. **[Scaffolding protein functional sites using deep learning ↗](https://doi.org/10.1126/science.abn2100)**Jue Wang, Sidney Lyayuga Lisanza, David Juergens et al.*486 citations*
64. **[Evidence for neutrino emission from the nearby active galaxy NGC 1068 ↗](https://doi.org/10.1126/science.abg3395)**R. Abbasi, M. Ackermann, Jenni Adams et al.*472 citations*
65. **[Metastable Dion-Jacobson 2D structure enables efficient and stable perovskite solar cells ↗](https://doi.org/10.1126/science.abj2637)**Fei Zhang, So Yeon Park, Canglang Yao et al.*466 citations*
66. **[CDK4 and CDK6 kinases: From basic science to cancer therapy ↗](https://doi.org/10.1126/science.abc1495)**Anne Fassl, Yan Geng, Piotr Siciński*464 citations*
67. **[Efficient and stable perovskite-silicon tandem solar cells through contact displacement by MgF x ↗](https://doi.org/10.1126/science.abn8910)**Jiang Liu, Michele De Bastiani, Erkan Aydın et al.*460 citations*
68. **[High thermoelectric performance realized through manipulating layered phonon-electron decoupling ↗](https://doi.org/10.1126/science.abn8997)**Lizhong Su, Dongyang Wang, Sining Wang et al.*459 citations*
69. **[Piezoionic mechanoreceptors: Force-induced current generation in hydrogels ↗](https://doi.org/10.1126/science.aaw1974)**Yuta Dobashi, Dickson R. Yao, Yael Petel et al.*457 citations*
70. **[Tunable structured light with flat optics ↗](https://doi.org/10.1126/science.abi6860)**Ahmed H. Dorrah, Federico Capasso*454 citations*
71. **[Engineering bacteria as interactive cancer therapies ↗](https://doi.org/10.1126/science.add9667)**Candice R. Gurbatri, Nicholas Arpaia, Tal Danino*447 citations*
72. **[Molecular signatures of antitumor neoantigen-reactive T cells from metastatic human cancers ↗](https://doi.org/10.1126/science.abl5447)**Frank J. Lowery, Sri Krishna, Rami Yossef et al.*447 citations*
73. **[Controlling the nucleation and growth kinetics of lead halide perovskite quantum dots ↗](https://doi.org/10.1126/science.abq3616)**Quinten A. Akkerman, Tan P. T. Nguyen, Simon Christian Boehme et al.*446 citations*
74. **[Harnessing the potential of nature-based solutions for mitigating and adapting to climate change ↗](https://doi.org/10.1126/science.abn9668)**Nathalie Seddon A*445 citations*
75. **[Rapid changes to global river suspended sediment flux by humans ↗](https://doi.org/10.1126/science.abn7980)**Evan Nylen Dethier, Carl Edward Renshaw, Francis J. Magilligan*442 citations*
76. **[Rational design of mixed-matrix metal-organic framework membranes for molecular separations ↗](https://doi.org/10.1126/science.abe0192)**Shuvo Jit Datta, Álvaro Mayoral, N.M. Srivatsa Bettahalli et al.*440 citations*
77. **[Nervous system consequences of COVID-19 ↗](https://doi.org/10.1126/science.abm2052)**Serena Spudich, Avindra Nath*435 citations*
78. **[The Huanan Seafood Wholesale Market in Wuhan was the early epicenter of the COVID-19 pandemic ↗](https://doi.org/10.1126/science.abp8715)**Michael Worobey, Joshua I. Levy, Lorena M. Malpica Serrano et al.*435 citations*
79. **[Ion-modulated radical doping of spiro-OMeTAD for more efficient and stable perovskite solar cells ↗](https://doi.org/10.1126/science.abo2757)**Tiankai Zhang, Feng Wang, Hak‐Beom Kim et al.*432 citations*
80. **[Universal assembly of liquid metal particles in polymers enables elastic printed circuit board ↗](https://doi.org/10.1126/science.abo6631)**Wonbeom Lee, Hyunjun Kim, In-Ho Kang et al.*430 citations*
81. **[A complete reference genome improves analysis of human genetic variation ↗](https://doi.org/10.1126/science.abl3533)**Sergey S. Aganezov, Stephanie M. Yan, Daniela C. Soto et al.*429 citations*
82. **[The emergent properties of the connected brain ↗](https://doi.org/10.1126/science.abq2591)**Michel Thiebaut de Schotten, Stephanie J. Forkel*429 citations*
83. **[The microbiome and gut homeostasis ↗](https://doi.org/10.1126/science.abp9960)**Jee‐Yon Lee, Renée M. Tsolis, Andreas J. Bäumler*428 citations*
84. **[Compositional texture engineering for highly stable wide-bandgap perovskite solar cells ↗](https://doi.org/10.1126/science.adf0194)**Qi Jiang, Jinhui Tong, Rebecca A. Scheidt et al.*425 citations*
85. **[Quantum optimization of maximum independent set using Rydberg atom arrays ↗](https://doi.org/10.1126/science.abo6587)**Sepehr Ebadi, Alexander Keesling, Madelyn Cain et al.*424 citations*
86. **[Global assessment of oil and gas methane ultra-emitters ↗](https://doi.org/10.1126/science.abj4351)**Thomas Lauvaux, Clément Giron, Matthieu Mazzolini et al.*423 citations*
87. **[Catalytic deconstruction of waste polyethylene with ethylene to form propylene ↗](https://doi.org/10.1126/science.add1088)**Richard J. Conk, Steven Hanna, Jake X. Shi et al.*419 citations*
88. **[Grazing and ecosystem service delivery in global drylands ↗](https://doi.org/10.1126/science.abq4062)**Fernando T. Maestre, Yoann Le Bagousse‐Pinguet, Manuel Delgado‐Baquerizo et al.*419 citations*
89. **[Multispecies forest plantations outyield monocultures across a broad range of conditions ↗](https://doi.org/10.1126/science.abm6363)**Yuhao Feng, Bernhard Schmid, Michel Loreau et al.*419 citations*
90. **[Low-temperature mineralization of perfluorocarboxylic acids ↗](https://doi.org/10.1126/science.abm8868)**Brittany Trang, Yuli Li, Xiao‐Song Xue et al.*418 citations*
91. **[Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function ↗](https://doi.org/10.1126/science.abl4290)**Gökçen Eraslan, Eugene Drokhlyansky, Shankara K. Anand et al.*405 citations*
92. **[From telomere to telomere: The transcriptional and epigenetic state of human repeat elements ↗](https://doi.org/10.1126/science.abk3112)**Savannah J. Hoyt, Jessica M. Storer, Gabrielle A. Hartley et al.*403 citations*
93. **[Late-stage diversification of indole skeletons through nitrogen atom insertion ↗](https://doi.org/10.1126/science.add1383)**Julia C. Reisenbauer, Ori Green, Allegra Franchino et al.*395 citations*
94. **[A photonic integrated circuit–based erbium-doped amplifier ↗](https://doi.org/10.1126/science.abo2631)**Yang Liu, Zheru Qiu, Xinru Ji et al.*390 citations*
95. **[Dynamic interplay between metal nanoparticles and oxide support under redox conditions ↗](https://doi.org/10.1126/science.abm3371)**Hannes Frey, Arik Beck, Xing Huang et al.*390 citations*
96. **[Spatial-CUT&Tag: Spatially resolved chromatin modification profiling at the cellular level ↗](https://doi.org/10.1126/science.abg7216)**Yanxiang Deng, Marek Bartošovič, Petra Kukanja et al.*388 citations*
97. **[Highly flexible and superhydrophobic MOF nanosheet membrane for ultrafast alcohol-water separation ↗](https://doi.org/10.1126/science.abo5680)**Li‐Hao Xu, Shen-Hui Li, Heng Mao et al.*382 citations*
98. **[Isospin magnetism and spin-polarized superconductivity in Bernal bilayer graphene ↗](https://doi.org/10.1126/science.abm8386)**Haoxin Zhou, Ludwig Holleis, Yu Saito et al.*378 citations*
99. **[Recovering wetland biogeomorphic feedbacks to restore the world’s biotic carbon hotspots ↗](https://doi.org/10.1126/science.abn1479)**Ralph J. M. Temmink, Leon P. M. Lamers, Christine Angelini et al.*378 citations*
100. **[Neutralization of SARS-CoV-2 Omicron by BNT162b2 mRNA vaccine–elicited human sera ↗](https://doi.org/10.1126/science.abn7591)**Alexander Muik, Bonny Gaby Lui, Ann-Kathrin Wallisch et al.*367 citations*

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